An analysis of Shenqi Dihuang decoction in treating proteinuria associated with anlotinib
Professor ZHU Chaofu has been engaged in the diagnosis and treatment of tumor in integrated TCM and Western medicine for many years,and has rich experience in the treatment of adverse reactions caused by various tumor surgery,radiotherapy,chemotherapy,targeting and other therapeutic means.Anlotinib hydrochloride is a small molecule multi-target tyrosine kinase inhibitor independently developed in our country,which has the characteristics of oral administration,high safety and easy portability,making it gradually applied in clinical practice,but numerous adverse reactions can not be ignored.In our department,proteinuria was the most obvious adverse reaction in oral anlotinib targeted therapy for tumor patients in the past.There are few methods to treat proteinuria associated with anlotion in Western medicine,and the clinical benefit is limited.Giving full play to the advan-tages of traditional Chinese medicine,Professor ZHU Zhaofu concludes that anrotinib-related proteinuria is closely related to the spleen and kidney by summarizing past experience and analyzing the symptoms of the patients,and the syndrome differentiation is deficiency of both Qi(气)and Yin(阴).In clinical practice,classic prescription Shenqi Dihuang decoction(参芪地黄汤)is used to relieve the symptoms and treat them according to syndrome differentiation,and good curative effect has been achieved.This article summarizes the characteristic prescription and experience of Professor ZHU Chao-fu in the treatment of anlotinib-related proteinuria based on clinical syndrome differentiation.However,as a third-line targeted anti-tumor drug,anlotinib has a limited number of patients and cannot be evaluated effectively.Secondly,the follow-up is mainly outpatient follow-up,patients decoct the prescribed traditional Chinese medicine themselves,there are large differences in individuation,and other factors also affect the drug efficacy,so in-depth and detailed research will continue in the later stage.
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维普
