目的:研究结肠息肉的中医证型分布,同时探讨其中医证型与病理类型及发病因素的相关性,旨在为结肠息肉临床辨证和中医防治提供依据.方法:通过回顾性研究的方法获取并整理结肠息肉患者的基本信息、中医证型、病理分型、血脂程度及结肠镜结果等信息,包括性别、年龄、饮食习惯、吸烟饮酒量、三酰甘油(Triglycerides,TG)、总胆固醇(Total Cholesterol,TC)、高密度脂蛋白(High-density Lipoprotein,HDL)、低密度脂蛋白(Low Density Lipoprotein,LDL)、息肉病理类型.统计分析结肠息肉中医证型与病理类型及发病因素之间的相关性.结果:①中医证型分布规律:大肠湿热证199例(39.5％)＞肝郁气滞证127例(25.2％)＞脾胃虚弱证101例(20.0％)＞瘀血内停证46例(9.1％)＞寒湿内阻证30例(5.9％).②结肠息肉患者年龄大多≥45岁,447例,占88.86％;饮食习惯以肥甘厚味为主,有208例,占41.35％;吸烟者232例,占46.13％;饮酒者136例,占27.04％.③结肠息肉患者中腺瘤性息肉患者295例,占58.65％,非腺瘤性息肉患者208例,占41.35％.④非高总胆固醇血症124例,占24.65％,高总胆固醇血症379例,占75.35％;非高甘油三酯血症136例,占27.03％,高甘油三酯血症367例,占72.97％;非高脂血症139例,占27.63％,高脂血症364例,占72.37％;非低高密度脂蛋白血症222例,占44.13％,低高密度脂蛋白血症281例,占55.87％.结论:结肠息肉中医证型以大肠湿热证多见.腺瘤性息肉中医证型以大肠湿热证为主,非腺瘤性息肉中炎性息肉以大肠湿热证为主,增生性息肉以肝郁气滞证多见,差异具有统计学意义(P＜0.05).不同证型高总胆固醇血症分布具有差异(P＜0.05),以大肠湿热证多见;不同证型高总胆固醇血症、高脂血症、低高密度脂蛋白血症分布无差异(P＞0.05).
A study on the correlation between TCM syndrome types,pathological types and pathogenic factors of colon polyps
Objective:To study the distribution of traditional Chinese medicine syndromes of colon polyps,and to explore the correlation between TCM syndrome types and pathological types as well as pathogenic factors,in order to provide the basis for clinical syndrome differentiation and TCM prevention and treatment of colon polyps.Methods:Through retrospective study,the basic information,TCM syndrome type,pathological type,blood lipid level and colonoscopy results of patients with colon polyps were obtained and sorted out,including gender,age,diet habits,smoking and drinking amount,triglyceride(TG),total cholesterol(TC),high-density lipoprotein(HDL),low-density lipoprotein(LDL),and pathological type of polyps.The correlation between traditional Chi-nese medicine syndromes,pathological types and pathogenic factors of colon polyps was analyzed statistically.Results:① The distribution law of TCM syndrome types:199 cases of large intestine damp-heat syndrome(39.5％)＞127 cases of liver Qi(气)stagnation syndrome(25.2％)＞101 cases of spleen and stomach weakness syndrome(20.0％)＞46 cases of blood stasis stopped syndrome(9.1％)＞30 cases of cold-damp internal resistance syndrome(5.9％).② Most patients with colon polyps were over 45 years old,there were 447 cases,account-ing for 88.86％;diet habits were a favor of rich food,there were 208 cases,accounting for 41.35％;a total of 232 cases were smokers,ac-counting for 46.13％;a total of 136 cases were drinking,accounting for 27.04％.③ Among the patients with colon polyps,295 cases were with adenomatous polyps,accounting for 58.65％,and there were 208 cases with non-adenomatous polyps,accounting for 41.35％.④ A total of 124 cases(24.65％)were non-hyper total cholesterolemia and 379 cases(75.35％)were hyper total cholesterolemia;A total of 136 cases(27.03％)were non-hyper triglyceride and 367 cases(72.97％)were hyper triglyceride;A total of 139 cases(27.63％)were non-hy-per LDLemic and 364 cases(72.37％)were hyper LDLemic;222 cases(44.13％)were non-hypo HDL emic and 281 cases(55.87％)were hypo HDL emic.Conclusion:In traditional Chinese medicine of colonic polyps syndromes,large intestine damp-heat syndrome are most common.Adenomatous polyps are mainly characterized by dampness and heat syndrome of large intestine,non-adenomatous polyps are mainly characterized by inflammation and dampness and heat syndrome of large intestine,while hyperplastic polyps are mostly character-ized by liver stagnation and Qi stagnation syndrome.There was statistical significance(P＜0.05).There are differences in the distribution of hyper TG among different syndrome types(P＜0.05),most of which are damp-heat syndrome of large intestine.There is no difference in the distribution of high TC,high LDL and low HDL among different syndrome types(P＞0.05).
Colon polypsTCM syndrome typePathological typePathogenic factorCorrelation study
万方数据
维普
