An analysis of prescriptions and medication rules of Professor SHI Zhexin in treating elderly iron deficiency anemia based on the Traditional Chinese Medicine Inheritance Support System
Objective:To analyze and summarize the prescriptions and medication rules of Professor SHI Zhexin in treating elderly iron deficiency anemia by data mining.Methods:The prescriptions from July 2019 to June 2022 of Professor SHI Zhexin were collected,which were prescribed in the hematology ward of First Teaching Hospital of Tianjin University of Traditional Chinese Medicine.The prescriptions were selected and input into the Traditional Chinese Medicine Inheritance Support System V2.5,and the selected prescriptions were analyzed by frequency analysis,association rules,complex entropy clustering analysis and other data mining methods.Results:A total of 149 prescriptions were collected,involving 152 kinds of Chinese herbs.Among them,warm and neutral herbs accounted for the majority in terms of medicinal natures.Sweet herbs accounted for a large proportion in terms of medicinal flavors.The herbs mainly entered into the spleen,stomach channels.The top ten herbs in use frequency were Chenpi(Pericarpium Citri Reticulatae),Fuling(Poria),Qingbanxia(Rhizoma Pinelliae),Dangshen(Radix Codonopsis),Jianshanzha(Fructus Crataegi),Chaojineijin(Endothelium Corneum Gigeriae Galli),Jiaoliushenqu(Massa Fermentata),Jiaomaiya(Fructus Hordei Germinatus),Gancao(Radix Glycyrrhizae),Wuweizi(Fructus Schisandrae Chinensis).The top five herbal combinations in use frequency were Qingbanxia-Chenpi,Qingbanxia-Fuling,Chenpi-Fuling,Qingbanxia-Chenpi-Fuling,Chenpi-Dangshen.A total of 18 core Chinese medicine combinations were excavated,and seven new prescriptions were obtained.Conclusion:Due to the special clinical characteristic of elderly iron deficiency anemia,which is weakness of five internal organs and sluggishness of Qi(气)and blood,traditional Chinese medicine need to highlight the nourishment when treating,especially pay attention to the nourishment of the spleen,stomach and heart.Warming the middle energizer,making spleen and stomach strong,recuperating Qi and blood,nourishing the mind are the basic methods.The above characteristics of prescriptions prescribed by Professor SHI can provide reference for the treatment of iron deficiency anemia in the elderly.
Elderly iron deficiency anemiaTraditional Chinese Medicine Inheritance Support SystemMedication rule