A retrospective cohort study on the clinical efficacy of the Fuzheng Xiaoliu plaster on liver cancer patients based on the real world of HIS system
Objective:based on real world analysis of the clinical efficacy and benefits of the Fuzheng Xiaoliu plaster(扶正消瘤贴)on liver cancer,this study provides research evidence and data support for future prospective research,and explores potential treatment methods for liver cancer and its complications.Methods:This study used a retrospective cohort study method,involving a total of 219 patients who were divided into the Xiaoliu plaster group and the control group based on whether they were treated with the Fuzheng Xiaoliu plaster.Cox regression analysis was used to explore the risk factors of survival indicators.VAS scores,Child-Pugh scores and PS scores before and after hospitalization were analyzed based on HIS medical records and liver function tests,and the number of adverse events related to the Fuzheng Xiaoliu plaster was counted.Results:In the baseline comparison of patients,after univariate Cox model analysis,it was found that 40-60 years old(P=0.012 2,HR=0.605)and hypertension(P=0.009 2,HR=0.558)were protective factors for liver cancer survival.The overall survival period of the Xiaoliu plaster group showed a trend of being lower than the control group,while the progression free survival period was significantly higher than the control group(P=0.003 7).Difference of the VAS score and PS score in the Xiaoliu plaster group were significantly better than the control group(P=0.007 4,P=0.005 8).The Child Pugh score in the Xiaoliu plaster group showed a downward trend after treatment,while the control group showed an upward trend.The incidence of adverse events in this study was 9.94％.Conuusion:The Fuzheng Xiaoliu plaster has more advantages in controlling disease progression,alleviating cancer pain,reducing Child-Pugh score,and improving quality of life,with high safety.
The Fuzheng Xiaoliu plasterLiver cancerRetrospective cohort studySurvival periodVisual analogue scale
万方数据
维普
