首页|基于中医传承计算平台分析王进东教授治疗失眠的用药规律

基于中医传承计算平台分析王进东教授治疗失眠的用药规律

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目的:总结王进东教授治疗失眠的用药规律,为临床用药和研究提供参考.方法:收集2017年1月-2021年12月王进东教授治疗失眠的病例处方,采用中医传承计算平台(V3.0)建立数据库,运用频数统计、关联规则等方法对高频药物、性味归经、组方规律进行统计分析.结果:共纳入300首处方,涉及药物112味,其中寒、温、苦、辛、甘为高频性味,脾经、肝经为高频归经,药物功效以清热药和补虚药为主;"龙骨-牡蛎""茯苓-白术"等为高频药物组合;通过聚类分析共提取出4个核心药物组合,且药物与病机契合.结论:运用中医传承计算平台对王进东教授治疗失眠的用药规律进行探索,结果能较客观地反映王进东教授治疗本病的学术思想及用药规律,对临床有一定的借鉴与参考价值.
An analysis of Professor WANG Jindong's medication rules in the treatment of insomnia based on T CM inheritance computing platform
Objective:To summarize Professor WANG Jindong's medication rule for insomnia,and to provide reference for clinical medication and research.Methods:The prescriptions of Professor WANG Jindong for the treatment of insomnia from January 2017 to December 2021 were collected,a database was established by the traditional Chinese medicine inheritance computing platform(V3.0),and the frequency statistics,association rules and other methods were used to analyze the high-frequency drugs,Medicinal properties and tastes,meridian affinity,and prescription patterns.Results:(1)A total of 300 prescriptions were included,involving 122 flavors of drugs,of which cold,warm,bitter,acrid,and sweet were high-frequency flavors,and the spleen and liver meridians were high-frequency returning meridians.The main efficacy of the included drugs was clearing heat and tonifying deficiency.(2)Longgu(Os Draconis)-Muli(Concha Ostreae),Fuling(Poria)-Baizhu(Rhizoma Atractylodis Macrocephalae)were high-frequency drug combinations.(3)A total of 4 core drug combinations were extracted through cluster analysis,and the pathogenesis was consistent.Conclusion:The research uses the traditional Chinese medicine inheritance computing platform to explore the medication rules of Professor WANG Jindong in the treatment of insomnia,and the results can more objectively reflect the academic thoughts and medication rules of Professor WANG Jindong in the treatment of this disease in clinical practice.

InsomniaSleep disordersTCM inheritance computing platformMedication ruleExperience

张国辉、王进东、王静诺、曾宪峰

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北京中医药大学深圳医院(龙岗),广东 深圳,518000

失眠 睡眠障碍 中医传承计算平台 用药规律 经验

第四批广东省名中医师承项目

粤中医函[2023]85号

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(16)