The medication rules of LYU Shaoguang in the treatment of threatened miscarriage based on data mining
Objective:To analyze the medication pattern of LYU Shaoguang,a famous Chinese medicine doctor in the treatment of threatened abortion,and to provide reference for clinical treatment.Methods:The cases prescriptions of threatened abortion from Director LYU Shaoguang were collected and sorted.After standardized and unified the names of Chinese medicine in the included prescription,the case data set was established by Microsoft Excel 2013.Firstly,data mining module of the Ancient and Modern Medical Case Cloud Platform was used to conduct frequency analysis of TCM drugs and their flavors,properties,meridians,and functions.Secondly,herbal group prescriptions were further analyzed through association rule analysis,cluster analysis and complex network analysis.Results:A total of 268 Chinese medicine prescriptions were included in this study,involving 88 types of herbal medicines.The top 10 herbs were Baizhu(Rhizoma Atractylodis Macrocephalae),Shanyao(Rhizoma Dioscoreae),Lianzi(Semen Nelumbinis),Qianshi(Semen Euryales),Tusizi(Semen Cuscutae),Fushen(Poria cum Radix Pini),Gouqizi(Fructus Lycii),Chenpi(Pericarpium Citri Reticulatae),Zhuru(Caulis Bambusae in Taenia)and Sangshen(Fructus Mori).The main effects of the herbal medicines are to calm the fetus,strengthen the spleen and tonify the kidneys.They are mostly moderate,warm,sweet,bitter or pungent.These drugs are mostly absorbed by spleen and kidney meridians.Twenty-two commonly used herbal combinations are identified by association rule analysis.Five herbal clusters are identified by cluster analysis.The results of complex network analysis showed that Baizhu,Shanyao,Lianzi,Qianshi,Tusizi,Fushen,Gouqizi,Chenpi,Zhuru,Sangshen and Mohanlian(Herba Ecliptae)had the highest correlation degree.Conclusion:In the treatment of threatened abortion,LYU Shaoguang follows the method of"treating the spleen and kidneys together",with simplified medication to harmony Chong-Ren(冲任)meridians to prevent miscarriage.
Threatened abortionMedication patternSpleen and kidney co-therapy
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NSTL
万方数据
