"肺主行水"理论在慢性阻塞性肺疾病气道黏液高分泌中的应用探讨

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中文摘要：慢性阻塞性肺疾病是一种以持续性气流受限为主要特征的慢性气道炎症性疾病.气道黏液高分泌是慢性阻塞性肺疾病重要临床特征,主要是由于气道受到长期炎症刺激,杯状细胞产生过多,导致黏液堆积,产生咳嗽、咳痰等临床表现.气道黏液高分泌的实质是津液的代谢失常,而"肺主行水"是指肺气通过宣发和肃降推动和调节全身的津液代谢.慢性阻塞性肺疾病是肺失宣降的病理表现,气道黏液高分泌则是"肺主行水"功能异常的体现.在治疗上,西医以减少黏液分泌、抑制炎症等为主;中医以调理肺气宣降、调节水液代谢为基本治疗原则."肺主行水"理论为慢性阻塞性肺疾病气道黏液高分泌的研究提供了新思路.

外文标题：Discussion on the application of the theory of"lung governing water metabolism"in the treatment of COPD airway mucus hypersecretion

外文摘要：C hronic obstructive pulmonary disease(COPD)is a chronic airway inflammatory disease characterized by persistent airflow limitation.Airway mucus hypersecretion is an important clinical feature of COPD,mainly due to long-term inflammatory stimulation of the airway,excessive production of goblet cells,resulting in accumulation of mucus,causing clinical manifestations such as cough and expectoration.The essence of airway mucus hypersecretion is the abnormal metabolism of body fluid,and"lung goveming water metabolism"means that the lung Qi(气)promotes and regulates the body fluid metabolism of the whole body through promoting and descending.COPD is a pathological manifestation of lung failure,and airway mucus hypersecretion is a manifestation of abnormal function of"lung governing water metabolism".In terms of treatment,western medicine mainly focuses on reducing mucus secretion and inhibiting inflammation;traditional Chinese medicine focuses on regulating the circulation of lung Qi and regulating water metabolism.The theory of"lung governing water metabolism"provides a new way of thinking for the study of airway mucus hypersecretion in COPD.

外文关键词：

Chronic obstructive pulmonary diseaseHypersecretion of airway mucusLung governing water metabolismRespiratory function

作者：

苗青、王岷、王珺、孙梦雪

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作者单位：

山东中医药大学,山东济南,250013

山东中医药大学第二附属医院,山东济南,250001

关键词：

慢性阻塞性肺疾病气道黏液高分泌肺主行水肺气宣发肃降

基金：

国家中医药管理局新型冠状病毒感染中医药应急专项山东省教育厅2022年山东省研究生优质教育教学资源项目山东省中医药管理局科技发展计划

项目编号：

2023伦审-KY-006SDYKC20220422017-118

出版年：

2024

DOI：

10.3969/j.issn.1674-7860.2024.17.014

中医临床研究

中华中医药学会

中医临床研究

影响因子：0.839

ISSN：1674-7860

年,卷(期)：2024.16(17)