Discussion on the rules of traditional Chinese medicine medication for coronary heart disease complicated with anxiety and/or depression based on data mining
Objective:To analyze the medication rules of TCM in the treatment of coronary heart disease complicated with anxiety and/or depression,so as to provide data reference for the clinical treatment.Methods:In this study,122 patients with coronary heart disease complicated with anxiety and/or depression were collected,and the TCM prescription database was established.Based on the cloud platform of ancient and modern medical records,the data was analyzed for medication frequency,distribution of four Qi(气),five flavors and meridians,association rules of Chinese medicine,and clustering analysis of high-frequency Chinese medicine.Results:A total of 122 TCM prescriptions involving 193 TCMs were included in this study,among which the top 10 most frequently used drugs were Gancao(Radix Glycyrrhizae),Banxia(Rhizoma Pinelliae),Chaihu(Radix Bupleuri),Danshen(Radix et Rhizoma Salviae Miltiorrhizae),Fuling(Poria),Gualou(Fructus Trichosanthis),Huangqi(Radix Astragali),Dangshen(Radix Codonopsis),Guizhi(Ramulus Cinnamomi),and Chuanxiong(Rhizoma Chuanxiong).The medicinal properties of included Chinese medicine for the treatment of coronary heart disease complicated with anxiety and/or depression was mainly warm,flat,slightly cold,and cold.The medicine flavor was mainly sweet,bitter,and pungent.The meridian tropism was mostly lung meridian,spleen meridian,liver meridian,and heart meridian.Four groups of association rule data were obtained,which were Huangqi-Danshen,Fuling-Banxia,Dangshen-Gancao,Zhiqiao(Fructus Aurantii)-Chaihu-Huangqin(Radix Scutellariae),and the cluster analysis of high-frequency used Chinese medicine finally obtained four clusters:Banxia,Fuling,Gancao,Dangshen,Baizhu(Rhizoma Atractylodis Macrocephalae);Gualou,Sanqi(Radix Notoginseng),Danshen,Huangqi;Chaihu,Zhike,Guizhi,Chuanxiong,Chishao(Radix Paeoniae Rubra).Conclusion:In the treatment of coronary heart disease complicated with anxiety and/or depression,the main treatment method of traditional Chinese medicine is to tonify Qi,activate blood circulation,regulate Qi and resolving phlegm.
NETL
NSTL
万方数据
