Systematic review and Meta-analysis of the correlation between TCM constitution types and coronary heart disease
Objective:To systematically evaluate the distribution of traditional Chinese medicine(TCM)constitution in patients with coronary heart disease,and to provide evidence-based reference for clinical prevention and treatment of coronary heart disease.Methods:A total of 8 database of China National Knowledge Infrastructure(CNKI),WanFang Da-tabase,Chinese sci-tech periodical full-text database(VIP),Chinese Biomedical Database(CBM),PubMed,The Cochrane Library,Embase and Web of science were searched from the establishment of each database to October 2022.Research literature on coronary heart disease and TCM constitution types that met the requirements was included,and the original literature data were extracted and the quality of the study was evaluated.Stata16.0 software was used to conduct a Meta-analysis of the included literatures.Results:A total of 15 studies were included,including 13 cross-sectional studies and 2 case-control studies.The total sample size was 5287,including 4977 patients with coronary heart disease and 310 patients in the control group.The Meta-analysis results of 15 studies on the correlation between CHD and TCM constitutiont ypes showed that Qi(气)-deficiency constitution 0.23(0.18,0.28),blood-sta-sis constitution 0.22(0.18,0.26)and phlegm-dampness constitution 0.19(0.15,0.22)accounted for the highest proportion in the CHD patients included in the study,which accounted for more than half of the total number.Subgroup analysis by region showed that blood stasis was the most common bias in South China and North China.The most common biased constitution in central China and Northwest China is Qi deficiency.The subgroup analysis by gender showed that Qi-stagnation was the highest bias in female pa-tients,accounting for 16.04%.The highest proportion of male patients was damp-heat,accounting for 14.41%,and men with damp-heat were more likely to suffer from coronary heart disease than women.Conclusion:Qi-deficiency,blood stasis and phlegm damp-ness are the main TCM constitution types of patients with coronary heart disease.The distribution of main TCM constitution types of patients with coronary disease in different regions is different,and the common constitution types of patients with coronary heart disease in different genders are also slightly different.
Coronary heartd iseaseTraditional Chinese medicine constitutionQi deficiencyBlood stasisMeta-analysis
万方数据
维普
