Curative effect observation of Heibai Tongzhi decoction combined with NB-UVB in the treatment of vitiligo
Objective:To explore the efficacy and safety of Heibai Tongzhi decoction(黑白同治汤)combined with NB-UVB irradiation in the treatment of vitiligo.Methods:116 patients with vitiligo treated in Binzhou Huahai Vitiligo Hospital were divided into the treatment group and the control group according to the random number table method.The treatment group received oral administration of Heibai Tongzhi decoction and the control group received oral administration of Bailing tablet(白灵片).Both groups were treated with NB-UVB for 6 months,and the white spot area,adverse reactions and recurrence were observed and recorded before treatment,3 months and 6 months after treatment,respectively,for comparison and analysis.Results:In this study,5 cases of shedding were excluded,with 56 cases in the treatment group and 55 cases in the control group,and there was no significant difference(P>0.05);After 3 months of treatment,the cure rate of the treatment group was 75.0％(42/56),and the total effective rate was 92.9％(52/56);the cure rate of the control group was 18.2％(10/55),and the total effective rate was 38.2％(21/55),and the differences were statistically significant(P<0.05);After 6 months of treatment,the cure rate of the treatment group was 89.3％(50/56),and the total effective rate was 98.2％(55/56),and the cure rate of the control group was 27.3％(15/55),and the total effective rate was 61.8％(34/55),and the differences were statistically significant(P<0.05).There was no statistically significant difference in the cure rate among patients of different types after 6 months of treatment(P>0.05);there was no statistically significant difference in the cure rate among patients of different parts after 6 months of treatment(P>0.05);After 6 months of treatment,there was no adverse reaction in the treatment group while the adverse reaction rate in the control group was 14.5％(8/55),and the difference was statistically significant(P<0.05);After 6 months of follow-up,there was no recurrence in the treatment group,while the recurrence rate in the control group was 16.4％(9/55),and the difference was statistically significant(P<0.05).Conclusion:Heibai Tongzhi decoction combined with NB-UVB irradiation has a definite effect on various types and different parts of vitiligo.This technique has high patient compliance,no adverse reactions,and no recurrence after consolidation,which is worthy of further clinical promotion.
VitiligoHeibai Tongzhi decoctionSymdrome differentiation and treatmentNB-UVBBailing Tablet
万方数据
维普
