An analysis of the medication rules of traditional Chinese medicine in the treatment of ectopic pregnancy in recent 15 years based on data mining
Objective:To explore the characteristics and compatibility rules of Chinese medicine in the treatment of ectopic pregnancy based on data mining technology.Methods:The literature about the treatment of ectopic pregnancy with Chinese medicine in the past 15 years was retrieved from the Chinese database,and a database was established after screening according to the inclusion and exclusion criteria.Excel software was used to statistically analyze the occurrence frequency,medicine properties,medicine tastes,meridian tropism,and category frequency of herbal medicines in the prescriptions.Then SPSS software was used for association rules and cluster analysis.Results:A total of 192 prescriptions were obtained,involving 136 kinds of traditional Chinese medicines.It was found that the most frequently used herbal medicines in Chinese medicine prescriptions were Chishao(Radix Paeoniae Rubra),Danshen(Radix et Rhizoma Salviae Miltiorrhizae),Ezhu(Rhizoma Curcumae)etc..Commonly used medicine categories were blood-activating and stasis-removing medicines,heat-clearing medicines and tonic medicines.The top three medicine properties in terms of usage frequency were slightly cold,bland and warm,and the top three medicinal flavors were bitter,pungent and sweet.In terms of meridian tropism,it was mainly liver meridian,spleen meridian and heart meridian.In the association analysis,there were 36 strong association rules of two-way and three-way,among which the highest support rate was Danshen-Chishao,Ezhu and Chishao-Sanleng(Rhizoma Sparganii).In the cluster analysis,there were four effective clustering groups.Conclusion:The basic methods of Chinese medicine in the treatment of ectopic pregnancy are blood-activating,stasis-removing,heat-clearing and mass-eliminating.The main Chinese medicines are blood-activating and stasis-removing,which are compounded with heat-clearing medicines and tonic medicines,focusing on the compatibility principle of pungent and warm with bitter and cold,and regulating the heart,liver and spleen together.The prescription of traditional Chinese medicine can be modified with Chishao,Danshen,Ezhu,etc..
Data miningEctopic pregnancyTraditional Chinese medicineMedication rule