首页|基于属性偏序探究《四圣心源》肝病方用药规律

基于属性偏序探究《四圣心源》肝病方用药规律

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背景:《四圣心源》为清代乾隆御医黄玉璐所著.此著作汇集《黄帝内经》《难经》《伤寒论》《金匮要略》之精华,蕴含深刻的中医学理论及临床经验.我们通过属性偏序的研究方法汇总《四圣心源》中治疗肝病的处方并进行分析,以探讨黄玉璐治疗肝病的思想和用药规律,有利于指导中医临床用药,传承中医学术经验与思想.目的:探究《四圣心源》中治疗肝病的方剂、用药规律.方法:运用属性偏序原理筛选《四圣心源》中肝病用方,将诸方药物划分为不同的属性类别,统计使用频次,并建立属性偏序关系,绘制属性偏序图.结果:从《四圣心源》中共筛选出肝病相关方剂12首,中药组成28味.分析发现《四圣心源》中治肝方药以桂枝、茯苓为重,药性侧重寒与温,药味偏苦、辛、甘之味.结论:黄玉璐认为诸病所生,皆因中气不足,土湿中生,土湿木郁即肝病的核心病机,故常以桂枝、茯苓为主.桂枝入于足厥阴肝经,条达之性与肝之条达相应,调畅木气;茯苓健脾燥湿,泻水燥土,以治土湿木郁之象.治疗肝病时需重视肝脾关系,以"培土疏肝"为主,培中焦脾胃之气,运化水湿,同时疏肝解郁,使肝气条达,多用桂枝、茯苓之药,注重调补中气,重视中焦,佐以半夏降胃、人参培补元气,事半功倍.
Research on the medication rules of liver disease prescription in Sisheng Xinyuan based on attribute partial order structure
Background:Sisheng Xinyuan(《四圣心源》)was written by HUANG Yulu,the imperial doctor of Qianlong in the Qing Dynasty.This book collects the essence of Huangdi Neijing(《黄帝内经》),Nanjing(《难经》),Shanghanlun(《伤寒论》)and Jingui Yaolue(《金匮要略》),and is a classic medical book combining theory with practice.The prescriptions in Sisheng Xinyuan that are used to treat liver disease were summarized.Research method of attribute partial order for analysis was applied.It is to explore HUANG Yulu treatment of liver disease thought and drug law.This is helpful to guide the clinical use of traditional Chinese medicine(TCM)and inherit the academic experience and thought of TCM.Objective:To investigate the medication rules for treating liver disease in Sisheng Xinyuan.Methods:According to the partial order principle of attributes,we screened the prescriptions of Sisheng Xinyuan for the treatment of liver diseases.We divided the traditional Chinese medicine of each prescription into different attribute categories,and then established the attribute partial order relationship and drew the attribute partial order diagram.Results:We screened 12 prescriptions from Sisheng Xinyuan,all of which were related to liver disease.A total of 28 traditional Chinese medicines were included in the prescriptions.According to the analysis,Guizhi(Ramulus Cinnamomi)and Fuling(Poria)were commonly used in the prescription for treating liver in Sisheng Xinyuan.Cold and warm medicine were often used.The medicine tastes always were bitter,pungent and sweet.Conclusion:HUANG Yulu believes that all diseases are born because of the lack of Zhongqi(中气),soil dampness from the center,soil dampness and wood depression is the core pathogenesis of liver disease.So Guizhi and Fuling are applied nin clinic.Guizhi treated the foot syncope Yin(阴)liver meridian.The nature of the plant echoes that of the liver,with regulating the wood Qi.Fuling can strengthen the spleen and remove dampness,water leaves and soil dry,in order to treat the image of soil dampness and wood depression.The treatment of liver disease needs to pay attention to the relationship between the liver and spleen,to"cultivate the soil and soothe the liver".The treatment can cultivate the spleen and stomach Qi,transport water and dampness,and at the same time soothe the liver and relieve depression,so that the liver Qi is reached.Guizhi and Fuling treat by recuperating the Zhongqi,pay attention to middle-Jiao(中焦),and get a good effect accompanied by Banxia(Rhizoma Pinelliae)and Renshen(Radix Ginseng).

Sisheng XinyuanAttribute partial order structureLiver diseaseMedication rule

刘逸藩、徐子皓、吴辉坤

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湖北中医药大学,湖北 武汉,430065

《四圣心源》 属性偏序结构 肝病 用药规律

吴寿善全国名老中医药专家传承工作室

P-20190117-0499

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(22)