首页|基于CiteSpace独活寄生汤治疗骨关节炎的可视化分析

基于CiteSpace独活寄生汤治疗骨关节炎的可视化分析

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目的:基于CiteSpace对独活寄生汤治疗骨关节炎的研究热点及趋势进行可视化分析,以了解该领域的研究现状、研究热点、作者、研究机构的合作网络并预测其未来发展趋势.方法:通过挖掘2000年1 月1日-2022年12月31日中国知网数据库中收录的独活寄生汤治疗骨关节炎的中文研究文献,采用Excel软件统计年度发文量,通过CiteSpace 6.1.R6软件构建作者和研究机构合作网络知识图谱,形成作者合作图、机构合作图、关键词聚类分析图等.结果:关于独活寄生汤治疗骨关节炎的研究数量呈波动上升且增幅愈趋高涨,以福建中医药大学为首的各大研究机构都在开展相关研究,并形成了以李西海、郑春松、吴广文和陈少青为代表的密切合作的研究团队.该类研究在中医学及中西医结合医学期刊上广泛发表.关键词共现显示骨关节炎出现频次最高,聚类分析形成13个标签,涉及临床研究类型、关节炎不同分型以及作用机制探索3个方面.研究热点以"针灸""炎症因子""临床疗效"等为主.独活寄生汤治疗骨关节炎的作用机制主要集中在抑制炎症因子和细胞凋亡、促进软骨细胞增殖、抑制软骨基质降解、氧化应激等途径.结论:独活寄生汤治疗骨关节炎的研究在临床应用领域不断拓展,并逐渐深入,研究内容向着其作用机制、作用靶点等方向发展,但是缺乏有深度的高质量临床试验,未形成多学科及多机构之间的紧密合作.
A visualization analysis of treating osteoarthritis disease with the Duhuo Jisheng decoction based on CiteSpace
Objective:To visualize and analyze the relevant literature on the treatment of osteoarthritis(OA)with the Duhuo Jisheng decoction(独活寄生汤)by means of CiteSpace,so as to understand the research status,research hotspots,authors,research institutions in this field and predict its future development tendency.Methods:Literature about treating OA with the Duhuo Jisheng decoction was retrieved from CNKI since January 1,2000 to December 31,2022.The Excel software was used to count the annual publication volume and major journals of the Duhuo Jisheng decoction in the treatment of OA.CiteSpace 6.1.R6 software was used to build knowledge graphs of author cooperation network and institution cooperation network,and form a keyword cluster graph.Results:The number of studies on the treatment of OA with the Duhuo Jisheng decoction showed a fluctuating upward trend.The major research institutions headed by the Fujian University of Traditional Chinese Medicine were conducting relevant research,forming a closely-cooperative research team represented by LI Xihai,ZHENG Chunsong,WU Guangwen and CHEN Shaoqing.The study was widely published in traditional Chinese medicine and the integrative medicine journals.The co-occurrence of keywords showed that the frequency of OA was the highest,and 13 tags were formed by cluster analysis,involving three aspects:clinical research types,different types of OA,and mechanism of action.The researches focus on acupuncture,inflammatory factors and clinical efficacy.The action mechanism of the Duhuo Jisheng decoction on OA is mainly concentrated in inhibiting inflammatory factors and cell apoptosis,promoting chondrocyte proliferation,inhibiting cartilage matrix degradation,oxidative stress,and other pathways.Conclusion:The research trend of the Duhuo Jisheng decoction in the treatment of OA shows that its scope of clinical application is gradually expanding,the research content is gradually developing towards the direction of its action mechanism and action targets.However,there is still a lack of in-depth high-quality clinical trials and close interdisciplinary and inter-institutional cooperation.

The Duhuo Jisheng decoctionOsteoarthritisVisual analysisBibliometrics

储涛、郭彬

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湖南中医药大学研究生院,湖南 长沙,410208

重庆市垫江县中医院,重庆,408300

独活寄生汤 骨关节炎 可视化分析 文献计量学

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(23)