One case of bullous pemphigoid plus lower extremity deep vein thrombosis
Bullous pemphigoid,as a type of autoimmune disease,is more common in elderly individuals.It is characterized by thick-walled blisters with clear fluid that are resistant to rupture.The histopathology shows subepidermal blisters,often accompa-nied by deposits of IgG and/or C3 along the basement membrane.The disease has a prolonged course,and can involve the entire body of severe cases,leading to systemic exhaustion.In Western medicine,glucocorticoids are commonly used as the first-choice treatment for this condition.However,prolonged use of steroids can lead to various complications,even multiple organ failure.How to relieve symp-toms and improve prognosis in clinical practice has become a major problem for dermatologists.In March 2023,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine admitted one case of bullous pemphigoid plus lower extremity deep vein thrombo-sis.After treatment in the integrative medicine,the skin lesions of the patient subsided and the lower extremity deep vein thrombosis grad-ually stabilized.This article reports the clinical diagnosis and treatment process of this patient,and discusses the potential association and preventive measures between bullous pemphigoid and lower extremity deep vein thrombosis,aiming to provide clinical reference.
Bullous pemphigoidLower extremity deep vein thrombosisSpleen deficiency and dampness accumulation syndrome