A discussion on modified Xiaoqinglong decoction combined with Tingli Dazao Xiefei decoction in the treatment of lung cancer-associated malignant pleural effusion
Lung cancer-associated malignant pleural effusion is a frequently encountered complication in advanced-stage lung cancer patients,which is difficult to cure and easy to relapse,and seriously affects the quality of life of patients.In Western medicine,thoracic aspiration and drainage,pleuropexy,thoracic thermoperfusion,intrapleural perfusion(chemotherapeutic drugs,biological response modulators),anti-angiogenic drugs (bevacizumab,recombinant human vascular endothelial growth factor inhibitors)and drug-loaded particles are the main treatment methods.Traditional Chinese medicine treatment is usually based on oral administration of traditional Chinese medicine decoction,acupoint application of traditional Chinese medicine,injection of traditional Chinese medicine preparation and acupuncture.In this paper,the efficacy of traditional Chinese medicine and pharmacological action of Western medicine of Xiaoqinglong decoction(小青龙汤)and Tingli Dazao Xiefei decoction(葶苈大枣泻肺汤)are systematically analyzed,and the therapeutic effect on lung cancer-associated malignant pleural effusion is expounded.In traditional Chinese medicine,its pathologic location is in the thoracoabdominal region,hence it is identified as"retention of body fluid",the syndrome differentiation is"fluid stasis in the thoracoabdominal region".The main therapeutic principles are warming Yang(阳),promoting lung and clearing dampness,which is supplemented by reinforcing the vital energy and anticancer,overall regulation,syndrome differentiation and treatment.Modified Xiaoqinglong decoction combined with Tingli Dazao Xiefei decoction is used in the treatment of lung cancer-associated malignant pleural effusion.Xiaoqinglong decoction and Tingli Dazao Xiefei decoction are well-known prescriptions from the classical Chinese medical texts of Shanghan ZabingLun(《伤寒杂病论》),are used in the treatment ofbronchial asthma,chronic obstructive pulmonary disease,heart failure,pleural effusion,malignant tumor and other diseases clinically with significant effects.In this study,it is mainly used in the treatment of patients with lung cancer-associated malignant pleural effusion.The treatment effect is satisfactory,the pain of patients is reduced,the quality of life of patients is improved,and the diagnosis and treatment ideas are provided for the later clinical treatment of lung cancer-associated malignant pleural effusion.
Malignant pleural effusionXiaoqinglong decoctionTingli Dazao Xiefei decoctionWarming Yang,promoting lung and clearing dampnessReinforcing the vital energy and anticancer
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