Treatment of middle and advanced colorectal cancer from the perspective of Jueyin
Objective:To explore the clinical significance of treating middle and advanced colorectal cancer from the perspective of Jueyin(厥阴),so as to provide TCM theoretical basis for the treatment of middle and advanced colorectal cancer from the perspective of Jueyin,and to guide the clinical treatment.Methods:Based on the study of TCM literature and the understanding of modern medicine on the middle and advanced colorectal cancer,the etiology and pathogenesis of middle and advanced colorectal cancer and the physiological and pathological characteristics of Jueyin are closely discussed.If middle and advanced colorectal cancer is prolonged and does not heal,it will deplete the body's healthy Qi(气),coupled with mood failure,liver Qi stagnation,Qi and blood obstruction,phlegm toxin coagulation,evil Qi will be detained in the intestinal tract and lead to cancer.Jueyin is the end of the channels and collaterals.Jueyin is the closure,and the main function is to absorb and conserve,which is to nourish Yin(阴)and release Yang(阳).If Jueyin is not shut,it can not nourish Yin and Qi,and Yin and Qi can not be hidden,Yang can not be born,and if Yin and Yang fail to connect,the function of viscera will be disordered,there would be the symptoms of mixed cold and heat.Results:The occurrence of middle and advanced colorectal cancer is often caused by injury to the liver and spleen due to prolonged depression resulting in the loss of the function of transportation and dispersal of liver and spleen,obstruction of Qi,accumulation of blood stasis and toxin,and immersion in the intestinal tract.The basic pathological position of middle and advanced colorectal cancer is Jueyin,and the pathogenesis is the disorder of Jueyin closure,so it is often manifested as the syndrome of mixed deficiency and accumulation.The treatment should pay attention to the combination of cold and warm,regulating Yin and Yang.Conclusion:In the clinical treatment of middle and advanced colorectal cancer,ZHANG Ji's Jueyin disease prescription—Wumei Wan(乌梅丸)recorded in Shanghan Lun(《伤寒论》)is recommended,and 1 case is attached.Wumei Wan is used to regulate the whole body's Qi movement,and tonify deficiency and reduce excess to regulate the deficiency and excess of viscera,so as to coordinate the functions of viscera and balance Yin and Yang.The clinical application of Wumei Wan in the treatment of middle and advanced rectal cancer has clinical guiding significance.
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