A randomized controlled study on the intervention of the Yehansu decoction on the fatigue of people with Qi deficiency
Objective:To discuss the clinical efficacy and safety of the Yehansu decoction(夜寒苏煎剂)on fatigue in patients with Qi(气)deficiency.Methods:A total of 120 patients were divided into three groups:the Yehansu(Radix Curcumae)group,the Dangshen(Radix Codonopsis)group,and the Solanum tuberdsm group,with 40 patients in each group.The patients were administered the Yehansu decoction,the Dangshen decoction,and the Solanum tuberdsm decoction,respectively.The dosage was set at one dose per day,with 2 bags taken 40 minutes after meals.After one month of treatment,the fatigue status,blood routine,urine routine,liver and kidney function-related indicators were evaluated.Results:The Fatigue Assessment Scale-14 scores was significantly decreased in the Yehansu group and the Dangshen group after intervention.The fatigue scores in both the Yehansu and Dangshen groups were significantly lower than in the Solanum tuberdsm group.The number of clinically controlled cases was higher in the Yehansu group than the Solanum tuberdsm group.The number of significantly effective cases was higher in both the Yehansu and Dangshen groups than the Solanum tuberdsm group.The number of ineffective cases was lower in both the Yehansu and Dangshen groups than the Solanum tuberdsm group(P＜0.05).After intervention,the Dangshen group had lower hemoglobin(Hb)levels than the Yehansu and the Solanum tuberdsm groups.The Yehansu and Solanum tuberdsm groups had higher aspartate aminotransferase(AST)levels than the Dangshen group.The Dangshen group had lower complement component 3(C3)levels than the Yehansu and the Solanum tuberdsm groups.The Yehansu group had higher complement component 4(C4)levels than the Dangshen group(P＜0.05).Conclusion:Yehansu can improve the fatigue status of individuals with Qi deficiency constitution without adverse effects.
万方数据
维普
