Overview of chronic obstructive pulmonary disease phenotype and its correlation with TCM syndrome type
Chronic obstructive pulmonary disease(COPD)is one of the major causes of disability and death in the world.The number of deaths from COPD in China ranks first in the world.The prevalence rate of COPD increases year by year,the mortality rate is high,and the economic burden and social burden of patients are heavy.In order to identify COPD early and provide individualized precision medicine for it,the COPD phenotype is proposed.Combining the COPD phenotype with TCM syndrome type can more accurately evaluate patients with COPD and help develop more personalized treatment plans for patients with COPD.It lays a good foundation for more individualized treatment of this disease in the future.The inflammatory cell phenotypes include eosinophil,neutrophil,lymphocyte and monocyte.Clinical symptom phenotype includes mild,moderate,severe chronic bronchitis type,emphysema type,bronchiectasis type,overlapping type,infrequent acute plus severe,acute plus severe,frequent acute plus severe;Imaging phenotypes include emphysema phenotype,small airway phenotype,with or without bronchial wall thickening;Acute exacerbation phenotypes include light and heavy antibiotic laziness,glucocorticoid-sensitive,glucocorticoid-dependent,glucocorticoid-resistant,etc.This paper reviews the phenotypes of chronic obstructive pulmonary disease,reviews the literature on the correlation between different phenotypes and TCM syndrome types,summarizes the association between each phenotype and TCM syndrome types,and summarizes the evidence-based medical evidence support for the phenotypes of chronic obstructive pulmonary disease and the correlation between TCM syndromes.
万方数据
维普
