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哈团结主任治疗桥本甲状腺炎甲减期经验撷萃

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桥本甲状腺炎(Hashimoto Thyroiditis,HT)是一种常见的由自身免疫功能失调引发的内分泌疾病之一,其中以胞浆或次黏液型甲状腺炎最为典型.这种病症首次由日本内科专家桥本内行于1912年命名并详细描述.在HT发病过程中,人体免疫系统出现异常,错误地攻击甲状腺组织,导致甲状腺功能逐渐减退.病情发展至一定阶段,患者会出现疲乏、体重增加、抑郁、肌肉关节疼痛等甲减症状.基于疾病的自身免疫性质,目前,西医针对HT甲减的治疗仍然缺乏直接针对疾病根本原因的方法,主要通过对症治疗,包括补充甲状腺激素和调节免疫系统来缓解症状和控制疾病的发展,治疗方法主要为甲状腺激素替代治疗法,如终身口服优甲乐,或者适当补充微量元素,如口服硒酵母片等.然而这种治疗手段需要患者有较高的依从性,称得上是一种"患者-医生契约"的治疗方式.可想而知,这样的治疗方式及其可能的不良反应给患者的生活质量带来了一定的影响,甚至对患者造成一定的心理压力.然而,HT的发病机制复杂,演变过程中脾胃功能减弱,肾气亏虚,脏腑功能失调.尽管西医治疗方式具有一定的疗效,但对于亚临床和轻、中度病例并无明显疗效.因此需要更多的疗法去协同,以提高治疗效果和患者生活质量.所以本研究提出以扶正祛邪为主要治疗手段,通过改善患者的临床症状,带来更好的治疗效果.与西医药物相比,此法较少产生不良反应,更能被患者接受和遵守.总体而言,扶正祛邪治疗法或许可以为HT的治疗打开新的可能.
Experience of Director HA Tuanjie in treating hypothyroidism in Hashimoto's thyroiditis
Hashimoto's thyroiditis(HT)is a common endocrine disorder,one of the diseases triggered by autoimmune dysfunction,with cytoplasmic or submucous thyroiditis being the most typical.This condition was first named and described in detail by the Japanese intemal medicine specialist Uchiyuki Hashimoto in 1912.During the development of Hashimoto's thyroiditis,the body's immune system becomes abnormal and mistakenly attacks the thyroid tissue,leading to gradual hypothyroidism.When the disease progresses to a certain stage,patients may experience symptoms of hypothyroidism such as fatigue,weight gain,depression,and muscle and joint pain.Based on the autoimmune nature of the disease,at present,the treatment of hypothyroidism in Western medicine for Hashimoto's thyroiditis still lacks a method that directly targets the root causes of the disease;instead,it is mainly based on symptomatic treatments,including supplementation of thyroid hormones as well as modulation of the immune system,to alleviate the symptoms and control the development of the disease,and the treatments are mainly thyroid hormone replacement therapy,(e.g.,lifelong oral administration of eugenol),or appropriate micronutrient supplementation,such as oral selenium yeast tablets.However,this treatment requires a high degree of patient compliance and is characterized as a"patient-physician contract".It is conceivable that such treatment and its possible side effects have a certain impact on the quality of life of patients,and even cause a certain degree of psychological pressure on patients.However,the pathogenesis of Hashimoto's thyroiditis is complex,and the spleen and stomach function is weakened,the kidney Qi is deficient,and the viscera function is dysfunctional in the evolution of the process.Although Westem medical treatment has a certain effect,it is not significantly effective in subclinical and mild to moderate cases.Therefore,more therapeutic dissynergies are needed to improve the therapeutic effect and the quality of life of patients.Therefore,this paper proposes that the main treatment method should be to support the normal function of the body and eliminate pathogenic factors.This approach can significantly relieve the patient's clinical symptoms and bring better treatment outcomes.Compared with Western medicine,this method produces fewer side effects and is more acceptable and complied with by patients.Overall,the method of supporting the normal function of the body and eliminating pathogenic factors may open up new possibilities for the treatment of HT.

Hashimoto's thyroiditisHypothyroidismSpleen-kidney yang deficiency typeIntegrated treatment of Chinese and Western medicine

张洒洒、哈团结、陈秀芝、李新安

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安徽中医药大学,安徽 合肥,230000

安徽中医药大学附属太和县中医院,安徽 阜阳,236600

桥本甲状腺炎 甲减期 脾肾阳虚型 中西医结合治疗

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(27)