Correlation between TLRs/NF-κB signaling pathway and the treatment of gonarthromen-ingitis based on the"deficiency and excess theory"
Gonarthromeningitis,a common disease in orthopedics and traditional Chinese medicine clinic,has no specific term in traditional Chinese medicine,but it can generally be classified into the categories of"arthralgia","tendon injury",and"bone bi syndrome".In modern medicine,it is clearly defined as a disease of the synovial membrane within the knee joint.With the vigorous development of Chinese medicine,its application in various clinical fields is becoming increasingly extensive.In orthopedics and traumatology of traditional Chinese medicine,the treatment approach of internal regulation and external application has demonstrated unique advantages in the treatment of gonarthromeningitis,and has been widely recognized by the medical community.However,the treat-ment methods of traditional Chinese medicine lack the support of modern scientific research theories,making it difficult to provide system-atic explanations.In recent years,the rapid development of biological science has provided new ideas for the modernization of traditional Chinese medicine.The discovery of signaling pathways and regulatory genes is of great significance to the therapeutic theory of traditional Chinese medicine.The TLRs/NF-κB signaling pathway is considered to be an important information for the treatment of gonarthromenin-gitis.Taking the"deficiency and excess theory"as the starting point,this paper combines the traditional TCM syndrome differentiation of zang-fu qi and blood with the TLRs/NF-κB signaling pathway in modern molecular science to reveal the expression mechanism of TLRs/NF-κB signaling pathway in the treatment of gonarthromeningitis with traditional Chinese medicine.The study intends to provide a pos-sible modern scientific theoretical basis for the treatment of gonarthromeningitis with traditional Chinese medicine,and contribute to the development of traditional Chinese medicine in the field of modern medicine.
"Deficiency and excess theory"GonarthromeningitisTLRs/NF-κB signaling pathway
万方数据
