The medication rule of oral Chinese medicine on pain after knee arthroplasty based on R language data mining
Objective:The medication rules of oral Chinese medicine on postoperative pain in knee arthroplasty was analyzed based on data mining technology.Methods:Relevant literature on treating postoperative pain in knee arthroplasty with oral Chinese medicine was screened by databases such as CNKI,Wanfang Data,VIP database,and SinoMed to establish a database of prescription medication for postoperative pain in knee arthroplasty.Excel was used to arrange and statistically analyze information on all prescriptions,including the used frequency,medical property and flavor,and meridian of single Chinese medicine.The frequency,association rules,and hierarchical clustering analyses were conducted by R language software.Results:A total of 80 prescriptions were included,involving 145 Chinese medicines with a total frequency of 984 times.The top 5 high-frequency Chinese medicines were Danggui(Radix Angelicae Sinensis),Chuanxiong(Rhizoma Chuanxiong),Honghua(Flos Carthami),Niuxi(Radix Achyranthis Bidentatae),and Taoren(Semen Persicae).The medical properties and flavors were mostly sweet,bitter,and warm,with the liver and spleen meridians being the main meridians.The association analysis suggested that Taoren,Honghua,Danggui,and Chuanxiong were the core Chinese medicines.Through cluster analysis,14 Chinese medicine combinations were obtained.Conclusion:The medication approach for postoperative pain in knee arthroplasty is to promote blood circulation and dredge meridians,and remove blood stasis and relieve pain in traditional Chinese medicine.Based on the results of syndrome differentiation and treatment,other Chinese medicines can be added or subtracted on the basis of the core prescription,providing a reference for future clinical treatment of the disease.
R language softwareData miningPostoperative pain in knee arthroplastyMedication rule