Exploring the treatment of polycystic ovary syndrome based on the theory of toxicity damages collaterals
Polycystic ovary syndrome is a common gynecological endocrine metabolic disease in women of reproductive age.In addition to hyperandrogenism,abnormal ovulation,ovarian polycystic changes,the disease is often accompanied by endocrine metabolic disorders such as insulin resistance,obesity,glucose and lipid metabolism disorders.The pathogenesis is complex,and its condition is lingering with a lengthy course.Western medicine focuses on symptomatic treatment in the treatment of PCOS,while TCM has unique advantages in the overall treatment of PCOS.According to the clinical manifestations,its pathogenesis can be summarized as long,stubborn,miscellaneous.The incidence of PCOS is closely related to liver,spleen and kidney.Due to congenital kidney deficiency,and acquired spleen deficiency and liver Qi(气)stagnation,the pathological products are accumulated and became poison over time,leading to collateral veins paralysis,then Qi and blood circulation in collateral veins is not smooth,and the functions of production and metaplasia of Qi and blood in Chong meridian(冲脉)and Ren meridian(任脉)is abnormal,leading to the loss of the nourishing of Qi and blood in uterus,which causes phlegm aggregation and stasis,resulting in PCOS finally.This view is consistent with the connotation of the poisoning-pathogenic disease theory and collateral-disease theory in TCM.Toxic pathogens can be classified into stasis toxin,phlegm toxin,turbidity toxin,and deficiency toxin according to different clinical characteristics of patients,therefore,on this basis,it is proposed that toxicity damages the collaterals is the core pathogenesis of PCOS.In the process of diagnosis and treatment,according to the characteristics of different stages of the disease,based on the intertwined pathological states of deficiency,phlegm,blood stasis,and turbid toxicity of liver,spleen,and kidney,guided by the principle of supporting vital energy,detoxifying,and clearing collaterals,the methods of nourishing kidney,strengthening spleen,dredging liver and so on are flexibly applied clinically.In addition,according to the different key points of PCOS,such as stasis toxicity obstructing collaterals,turbid toxicity damaging collaterals,deficiency toxicity damaging collaterals,kidney deficiency,liver deficiency,and spleen deficiency,the treatment based on syndrome differentiation is adopted,and attention is paid to the application of insect drugs,rattan drugs and other collagal-regulating drugs,aiming at expanding new ideas for clinical treatment of the disease.
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