A study on the distribution feature of TCM syndrome of pulmonary infection caused by multidrug-resistant bacteria in syndrome differentiation system of six meridians
Objective:To summarize and analyze the six meridians syndrome differentiation and distribution of hospitalized pulmonary infection patients with multidrug-resistant bacteria.Methods:Using the method of retrospective analysis,this study sorted out the basic situation,main clinical symptoms and signs of patients with pulmonary infection with multidrug-resistant bacteria hospitalized in Panyu District traditional Chinese medicine hospital from 2018 to 2021,and judged their six meridians syndrome differentiation.The syndrome types,sputum bacterial culture and drug sensitivity were comprehensively analyzed.Results:A total of 183 patients were included,with 188 strains of multidrug-resistant bacteria,among which a total of 163 strains of Gram-negative bacteria accounted for 86.70%,and 25 strains of Gram-positive bacteria accounted for 13.30%.The most common ones were Acinetobacter baumannii(64 strains),Pseudomonas aeruginosa(61 strains),and Klebsiella pneumoniae(26 strains),with a total of 151 strains of the three strains,accounting for 80.32%of the total strains.The syndrome differentiation of the six meridians was mainly based on the Yang meridian(阳经)type.Among them,100 cases of single meridian syndrome accounted for 54.64%,mainly including Shaoyang(少阳)syndrome,Shaoyin(少 阴)syndrome,and Yangming(阳明)syndrome,accounting for 51.11%of six meridian syndrome types.The main syndrome types of the two meridians were Taiyang(太阳)-Yangming syndrome,Shaoyang-Yangming syndrome,and Shaoyang-Shaoyin syndrome.The number of cases of multi-resistant Gram-positive bacteria was low,and Gram-negative bacteria were more common in Shaoyang and Shaoyin syndromes,but there were more cases of Taiyang-Yangming syndrome and Shaoyang-Yangming syndrome than the rest of the syndromes.In the syndrome types of positive bacteria,the positive bacteria of Shaoyang syndrome and Shaoyin syndrome accounted for a large proportion,followed by Yangming syndrome and Taiyang-Yangming syndrome.Pseudomonas aeruginosa infection mostly existed in patients with Taiyang syndrome and Yangming syndrome,while Acinetobacter baumannii infection mostly existed in patients with Shaoyang syndrome and Shaoyin syndrome.There were significant differences between the two in syndromes(P<0.01).Escherichia coli infection mostly existed in patients with Shaoyang syndrome,with a certain significant difference(P<0.05).There was no significant statistical difference between Staphylococcus aureus infection and Klebsiella pneumoniae infection in TCM syndrome classification(P>0.05).Conclusion:The six meridians syndrome types of hospitalized patients with pulmonary multidrug-resistant bacteria infection have a certain correlation with the strains of infection.Generally,the three Yang meridians syndrome types are dominant.It is suggested that the Yang meridian syndrome should be paid attention to in the diagnosis and treatment of pulmonary multidrug-resistant bacterial infection.
Syndrome differentiation of six meridiansConstitution of TCMMulti-drug resistant bacteriaLung infection