首页|基于数据挖掘探讨运用"伏风理论"治疗儿童疾病的用药规律

基于数据挖掘探讨运用"伏风理论"治疗儿童疾病的用药规律

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目的:应用数据挖掘技术研究在"伏风理论"指导下儿童疾病的具体用药规律,为进一步研究中医药治疗小儿疾病提供临床思路.方法:以"儿科""中医""伏风理论""中医药"为关键词,检索中国知网、万方、中文社会科学引文索引、维普数据库等平台,选取2009年-2023年发表的与伏风理论相关的方剂并创建数据库,采用Excel 2021、SPSS Modeler 18、SPSS 26.0软件对纳入的中药处方进行频次分析、药物性味归经分析、药物关联规则及聚类分析.结果:共筛选出100个处方,涉及194味中药,使用频次≥15的有甘草、防风、麻黄、蝉蜕、炙甘草、僵蚕等;所用药物以温性药为主,药味以甘、辛、苦为主,归经以归肺经为主;地肤子及蒺藜体现了较强的关联性.结论:在"伏风理论"指导下治疗儿童疾病的处方中药物的四气以温性为主,其次为寒性,药味多为辛、甘、苦,归经主要为肺经、肝经和脾经,功效为消风宣肺、息风止痉、清热凉血,为儿科临床医生提供基于"伏风理论"的用药规律.
The medication rule of the Fufeng theory in treating childhood diseases based on data mining
Objective:To apply data mining technology to study the specific medication rules for the treatment of childhood diseases under the guidance of Fufeng(伏风)theory,providing more clinical ideas for further research on treating childhood diseases in traditional Chinese medicine.Methods:With pediatrics,traditional Chinese medicine,Fufeng theory and Chinese medicine as keywords,CNKI,Wanfang,Chinese Social Sciences Citation Index and VIP databases were searched to select the prescriptions related to Fufeng theory published from 2009 to 2023 to create a database.Then Excel 2021,SPSS Modeler 18 and SPSS 26.0 were used to analyze the used frequency,medicinal property and taste and meridian affinity analyses,association rule analysis and cluster analysis of the included TCM prescriptions.Results:A total of 194 Chinese herbs were selected from 100 TCM prescriptions.Gancao(Radix Glycyrrhizae),Fangfeng(Radix Saposhnikoviae),Mahuang(Herba Ephedrae),Chantui(Cicada slough),Zhi Gancao(Roasted Radix Glycyrrhizae),Jiangcan(Bombyx Batryticatus)and so on were used more than 15 times.The main used drugs were warm drugs,the main medicinal tastes were sweet,pungency and bitter,and the main meridian affinity was lung meridian.There was a strong correlation between Difuzi(Fructus Kochiae)and Jili(Fructus Tribuli).Conclusion:In the prescriptions of treating childhood diseases under the guidance of Fufeng theory,the medicinal properties are mainly sweet,followed by cold,and the medicinal tastes are mainly pungency,sweet and bitter.The main affinity meridians are lung meridian,liver meridian and spleen meridian,and the effect is to dissipate wind and publicize lung,soothe wind and prevent spasticity,and clear heat and cool blood,so as to provide medication rules based on Fufeng theory for pediatric clinicians.

Data miningTraditional Chinese medicineChildrenFufeng theoryMedication rule

何怡、王昕、邓宗霞

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成都中医药大学附属医院,四川 成都,610000

绵阳市中医医院,四川 绵阳,621000

数据挖掘 中医药 小儿 伏风理论 用药规律

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(31)