A review on heat-clearing and detoxifying Chinese medicines in the treatment of malignant tumor
Heat poison is also known as fire poison or warm poison.Huangdi Neijing Taisu(《黄帝内经太素》):After fire poison enters into the body,bones become withered,meridians are broken and purulent,called the disease of evil fire,which embodies the fierce of heat toxin disease.The pathogenesis theory of cancer toxicity in modern TCM oncology emphasizes that cancer toxicity is mainly formed by a series of pathogenesis evolution of heat,phlegm,stasis and deficiency.The accumulation of heat toxicity is one of the pathogenesis that causes the formation and spread of malignant tumors.At the same time,the mechanical compression of the tumor leads to the pressure or obstruction of the organ lumen and blood vessels,and the inflammation or infection caused by it is also one of the factors that promote the deterioration and development of the tumor.Heat-clearing and detoxifying Chinese medicine is bitter and cold,can relieve the clinical symptoms caused by various heat toxicity and fire toxicity stasis,and reduce inflammation.Besides,it has the advantages of multiple targets,low price and broad research prospect of traditional Chinese medicine,which runs through the whole process of malignant tumor prevention and treatment.Therefore,heat-clearing and detoxification drugs have unique advantages in the prevention and treatment of malignant tumors.Recent theoretical,clinical and experimental studies on the treatment of malignant tumors with heat-clearing detoxifying Chinese medicines are summarized and analyzed,and it is found that it mainly plays an anticancer role by regulating signal pathways,inhibiting tumor cell proliferation,inducing cell apoptosis,enhancing immune function,improving tumor inflammatory microenvironment,reversing cell multi-drug resistance,inhibiting tumor angiogenesis,alleviating adverse reactions after chemotherapy,relieving cancer pain,etc..At the same time,there are risks of adverse reactions to the digestive system and neurotoxicity caused by improper use.In summary,through the summary and analysis of relevant literature,this paper summarizes the positive role and related risks of heat-clearing and detoxification drugs in the prevention and treatment of malignant tumors,in order to provide certain basis and reference for clinical diagnosis and treatment of the disease.
Cancer toxinHeat poisonClearing heat and detoxifyingMalignant tumorResearch progress
万方数据
维普
