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糖尿病肾病与气虚体质的相关性研究进展

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糖尿病肾病作为糖尿病的主要并发症,严重威胁患者健康。相关文献表明,气虚体质是发生糖尿病肾病的重要体质类型。文章综合分析近十年来的理论研究、实验研究、临床研究,探讨气虚体质与糖尿病肾病的相关性。研究发现,气虚质由于元气不足表现为生理功能低下,与糖尿病肾病的高发病率和进展密切相关。气虚体质的形成与先天禀赋、后天因素如年龄、饮食、劳逸、情志等密切相关。在中医学中,气虚体质通过影响肺、脾、肾功能可能促进病理产物如痰湿、瘀血的形成,加剧糖尿病肾病病程。在治疗策略上,文章归纳了中医治疗糖尿病肾病的多种方法,包括方药、针灸、食疗等,强调调整和增强机体元气,采用益气健脾、补肾固精、活血化瘀的治疗原则,以调和气血,改善症状,延缓疾病进展。实验研究进一步揭示了气虚体质与糖尿病肾病易感性的生物学联系,为中医治疗方法提供了科学依据。此外,文章还讨论了不同病程阶段糖尿病肾病患者的体质类型差异,以及地域、年龄、生活习惯等因素对体质分布的影响。最后,文章提出了未来的研究方向,包括扩大样本量、深入研究气虚体质的生理生化指标、利用现代科学技术探索气虚体质与糖尿病肾病的内在机制,以及开展更多中医治疗方法的临床研究。这些研究将为糖尿病肾病的预防和治疗提供更为精准的策略。
A review on the correlation between diabetic nephropathy and Qi-deficiency constitution
Diabetic nephropathy(DN),as the main complication of diabetes,seriously threatens the health of patients.Relevant literature shows that Qi-deficiency(气虚)constitution is an important constitution type of diabetic nephropathy.Through a comprehensive analysis of the theoretical research,experimental research and clinical research in the past ten years,this paper discusses the correlation between Qi-deficiency constitution and DN.It was found that Qi-deficiency manifested as low physiological function due to insufficient vitality,which was closely related to the high incidence and progression of DN.The formation of Qi-deficiency constitution is closely related to innate endowments,acquired factors such as age,diet,work and rest,and emotions.In traditional Chinese medicine,Qi-deficiency constitution may promote the formation of pathological products such as phlegm dampness and blood stasis,and aggravate the course of DN by affecting lung,spleen and kidney functions.In terms of treatment strategies,this paper summarized various methods of TCM treatment of DN,including prescriptions,acupuncture,diet,etc.,emphasizing the adjustment and enhancement of body vitality,the therapeutic principles of tonifying Qi(气)and strengthening spleen,tonifying kidney and reinforcing essence,and promoting blood circulation to remove blood stasis,in order to harmonize Qi and blood,relieve symptoms,and delay disease progression.The experimental study further revealed the biological relationship between Qi-deficiency constitution and DN susceptibility,and provided scientific basis for TCM treatment.In addition,this paper also discussed the difference of physical types of DN patients at different stages,and the influence of geographical,age,living habits and other factors on constitution type distribution.Finally,this paper put forward future research directions,including expanding the sample size,further studying the physiological and biochemical indexes of Qi-deficiency constitution,using modern science and technology to explore the internal mechanism of Qi-deficiency constitution and DN,and carrying out more clinical studies on TCM treatment methods.These studies will provide more accurate strategies for the prevention and treatment of DN.

Diabetic nephropathyQi-deficiency constitutionBody-disease correlation

吴甜婧、章莹、王飞

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江西中医药大学临床医学院,江西 南昌,330004

江西中医药大学中医学院,江西 南昌,330004

江西中医药大学院士工作站,江西 南昌,330004

糖尿病肾病 气虚质 体病相关

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(32)