Treating Henoch-Schonlein purpura nephritis based on the six-meridian hidden pathogen theory
Henoch-Schonlein purpura nephritis often recurs,is prolonged and difficult to heal,and TCM believes that this disease is closely related to hidden pathogen.Based on long-term clinical experience,the author believes that the pathogenesis of Henoch-Schonlein purpura nephritis lies in the pathogen hidden in Jueyin(厥阴),causing Yin(阴)deficiency and hidden heat,which is easy to relapse when infected with new pathogenic factors.The pathogenesis characteristics of Henoch-Schonlein purpura nephritis were discussed from three aspects:Jueyin meridians,Yinyang(阴阳),and Zangfu(脏腑).The Jueyin meridians are the pathways of pathogen.The nature of"one Yin(阴)"causes hidden pathogen.The pathogen lurks in Jueyin,and the wind and fire is formed.It is easy to stagnate and stasis,easy to enter and hard to exit,easy to accumulate and form,and easy to attack.However,Shaoyang(少阳)contains the Qi(气)of germination,which can be entrusted to dispel the pathogen,and there is a way to attract the pathogen out here.Therefore,the principle of dispelling pathogenic factors and strengthening the healthy Qi is applied to nourish Shaoyin(少阴)meridians and clear Jueyin meridians,so that the pathogenic factors can be removed from Shaoyang meridians.Guomin Jian(过敏煎)is the prescription for treating the diseases of the two meridians of Jueyin and Shaoyang,which can hold out and clear the pathogen at same time.In clinic,the Erzhi Dihuang decoction(二至地黄汤)plus Guomin Jian can be applied.In the acute attack period,pathogen is mostly caused by the new wind,heat,and poison,the products nourishing Yin can be slightly reduced,and Shengjiang San(升降散)with Yinqiao San(银翘散)can be given to increase its power of clearing heat and dispelling pathogen.During the clinical remission period,the residual pathogen obstructs the kidney veins,and removing blood stasis products such as Qiancao(Radix Rubiae),Zicao(Radix Arnebiae),Chishao(Radix Paeoniae Rubra),Taoren(Semen Persicae)can be added.During the recovery period,it is necessary to strengthen the body.Qi is damaged because of long course,and Huangqi(Radix Astragali),Dangshen(Radix Codonopsis),Baizhu(Rhizoma Atractylodis Macrocephalae)can be given to supplement the deficiency and strengthen the surface.At the end of this article,one case is listed in order to provide new diagnosis and treatment ideas for the clinical treatment of Henoch-Schonlein purpura nephritis.
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