首页|李建英教授运用升阳益胃汤加减治疗脾肾气虚兼湿热型难治性肾病综合征经验

李建英教授运用升阳益胃汤加减治疗脾肾气虚兼湿热型难治性肾病综合征经验

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难治性肾病综合征病情反复发作、久治难愈,并发症发生风险高,肾脏损害呈进行性加重,长期蛋白尿是进入终末期肾病的危险要素。李建英教授是医学博士,山东省名中医药专家,齐鲁卫生与健康领军人才,从事中医肾病工作近30年,积累了丰富的临床经验。基于李杲(号东垣)脾胃内伤论,李建英教授认为"脾肾气虚,元气不足"是蛋白尿久治难愈的病机根本,湿热久蕴、阴火内生是病程缠绵的主要因素。难治性肾病综合征患者病久体虚,脾胃中气不足,气陷于下,升举无力,浊阴下降,下注乘肾,肾气虚耗,元气虚损不得充养;另患者先天之气不足,机体无以固摄升提,精微下泄,致元气生化不足。脾肾气虚,清阳不升,湿热之邪蕴蒸,阴火妄动,乘其土位,日久灼伤肾络,亦损及元气。阴火上冲则元气更伤,加重脾肾气虚,精微下流,虚、火、湿三因交结,循环往复,耗伤元气,以致水肿、蛋白尿难消。临床应用升阳益胃汤加减治疗难治性肾病综合征,从固护脾肾、升阳除湿、消散阴火着手,以恢复脾胃气化之枢机,使清阳得升,水谷化为精微,滋养肾脏,肾气得复,湿热得祛,阴火难生,精微物质得以输布正常,减轻水肿、蛋白尿,缓解病情,临床取得满意疗效。
Professor LI Jianying's experience in treating refractory nephrotic syndrome of the spleen-kidney Qi deficiency and damp-heat syndrome with the Shengyang Yiwei decoction
Refractory nephrotic syndrome is recurrent and refractory to treatment,has a high risk of complications,and progressively worsens renal damage.Long-term proteinuria is a risk factor for end-stage renal disease.Professor LI Jianying as a doctor of medicine,a famous TCM expert in Shandong Province,and a leading talent in Qilu,has been engaged in TCM nephrology for nearly 30 years,and has accumulated rich clinical experience.Based on LI Gao's theory of internal injury to the spleen and stomach,Professor LI Jianying believes that spleen and kidney Qi(气)deficiency and lack of vitality are the root causes of refractory proteinuria for a long time,and the long-term accumulation of damp-heat and the endogenous generation of Yin(阴)and fire are the main factors for the lingering course of the disease.Patients with refractory nephrotic syndrome have been ill for a long time and have weak body,with insufficient Qi in the spleen and stomach,turbidity Yin descends and oppresses the kidneys,resulting in kidney Qi deficiency,and vitality cannot be replenished.In addition,the patient's congenital Qi is insufficient,and the body is unable to fix and raise,and the nutrient substance flows downward,resulting in insufficient biochemistry of vitality.The spleen and kidney Qi is deficient,the Qingyang(清阳)does not rise,the evil essence of dampness and heat is steaming,and the Yin fire are reckless,buming the kidney and meridians for a long time,and damaging the vitality.If the Yin fire rushes upward,the vitality will be more injured,aggravating the spleen and kidney Qi deficiency,and the three causes of deficiency,fire and dampness will intersect,and the cycle will be repeated,depleting the vitality,resulting in edema and proteinuria.The Shengyang Yiwei decoction(升阳益胃汤)was used clinically to treat refractory nephrotic syndrome,starting from the solid protection of the spleen and kidney,promoting Yang and dehumidification,and the dissipation of Yin fire,in order to restore the cardinal of spleen and stomach gasification,so that the Qingyang can be raised,the water valley can be turned into nutrient substance to nourish the kidneys,the kidney Qi can be restored,the damp-heat can be dispelled,the Yin fire is difficult to grow,the nutrient substances can be transmitted normally,and edema and proteinuria can be alleviated.The clinical satisfactory effect has been achieved.

Refractory nephrotic syndromeThe Shengyang Yiwei decoctionSpleen and kidneyDamp-heatYin fire

王素雅、王佳玉、李建英

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山东中医药大学,山东 济南,250014

即墨区中医医院,山东 青岛,266299

青岛大学附属青岛市海慈医院/青岛市中医医院,山东 青岛,266033

难治性肾病综合征 升阳益胃汤 脾肾 湿热 阴火

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(32)