An analysis of medication and point selection rules of epilepsy in children based on data mining
Objective:Based on data mining,the rules of medication and point selection for pediatric epilepsy was discussed to provide reference for the combination of acupuncture and medicine therapy for pediatric epilepsy.Methods:The literature in CNKI,Wanfang data and VIP database from the establishment of the database to May 2023 was retrieved,the prescription data was standardized to establish a database,and the ancient and modern medical record cloud platform(V2.2.3)was used to analyze clinical syndrome type,syndrome element,medication,and point selection.Results:The study included a total of 267 clinical trials and medical cases that met the criteria,involving 233 prescription formulas with 360 different medicines.The most common syndrome type was phlegm-wind obstruction syndrome,high-frequency medicinal ingredients included Shichangpu(Rhizoma Acori Tatarinowii),Fuling(Poria)and Tianma(Rhizoma Gastrodiae).The most commonly used medicinal combination was Shichangpu-Dannanxing(Arisaema Cum Bile),with effects of calming the wind,stopping convulsions and phlegm removal.Cluster analysis of core medicines obtained 8 groups of medicinal combinations.A total of 48 acupuncture and massage prescriptions were included,involving 161 acupoints or massage techniques,with the high-frequency acupoints of Baihui(DU20),Dazhui(DU14),and Zusanli(ST36).Prescriptions often were composed of Baihui with Taichong(LR3),Zusanli with Fengchi(GB20),and other acupoints.Conclusion:Pediatric epilepsy is often related to internal diseases,with the spleen and liver as the main affected organs,and the nature of the disease is mainly phlegm,obstruction,and wind,which is related to the physiological characteristics of children such as excess of liver and insufficiency of spleen.In terms of Chinese medicine treatment,doctors often use mild medicinal ingredients,combining with cold and warm medicine,with the five flavors of pungent,sweet,and bitter.The medicinal ingredients mainly flowed into the liver,lung,spleen,and heart meridians.Calming liver and wind-extinguishing drugs and tonics were the categories of high-frequency medicinal ingredients.The acupoints were often on the governing vessel and bladder meridian.In summary,modern doctors,based on their understanding of pediatric epilepsy,use medicinal ingredients and acupoints to not only awake the brain and open the orifices but also remove phlegm,unblock the collaterals,and nourish the heart to calm the spirit.
Epilepsy in childrenData miningDrug use ruleRule of point selectionTraditional Chinese medicine
万方数据
维普
