首页|基于张锡纯大气理论论治慢性阻塞性肺疾病合并肌少症

基于张锡纯大气理论论治慢性阻塞性肺疾病合并肌少症

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慢性阻塞性肺疾病(简称慢阻肺)以持续存在的气流受限和相应的呼吸系统症状为主要特征,是呼吸科常见的慢性气道疾病,也是一种复杂的多系统疾病,具有多种多样的肺内外表现,这些表现会进一步加重慢阻肺的危险因素,影响其预后.肌肉减少症(简称肌少症)是慢阻肺的常见并发症,其主要临床表现为与增龄相关的肌肉质量和力量下降,通过影响呼吸肌群和非呼吸肌群限制机体的活动和耐力,可严重影响慢阻肺的预后.慢阻肺合并肌少症的发病机制被大多数学者认为与全身炎症反应、氧化应激、骨骼肌代谢紊乱、糖皮质激素应用及营养不良等相关,现有疗法的临床治疗效果并不理想.慢阻肺合并肌少症归属于中医"肺胀"和"痿证"范畴,笔者基于张锡纯大气理论,结合《医学衷中参西录》中对大气生成和功能的描述,深入探寻慢阻肺合并肌少症的治疗新思路,认为大气虚损下陷导致全身脏腑气化功能失常,痰瘀内生是根本病因,以痰、瘀、虚为主要病机,大气虚衰为本,痰瘀阻滞为标,宗气虚衰贯穿始终,通过论述益气升陷、调和营卫、五脏同调、助气祛痰化瘀等治疗原则,从中医学观点探讨慢阻肺合并肌少症的治疗方法,为临床诊治提供富有中医特色和理论依据的综合方案,为改善患者预后和生活质量提供参考.
Treating chronic obstructive pulmonary disease plus sarcopenia based on the pectoral Qi theory of ZHANG Xichun
Chronic obstnictive pulmonary disease(COPD)is mainly characterized by persistent airflow limitation and the corresponding respiratory symptoms.It is a common airway disease in the Respiratory Department,and is also a complex multi-system disease,with a variety of internal and external pulmonary manifestations,which may further aggravate the risk factors of COPD and affect its prognosis.Sarcopenia is a common complication of COPD,with the decline of muscle mass and strength associated with aging as the main clinical manifestation.The disease limits body activity and endurance by affecting respiratory and non-respiratory muscle groups,and can seriously affect the prognosis of COPD.The pathogenesis of COPD plus sarcopenia is considered by most scholars to be related to systemic inflammatory response,oxidative stress,skeletal muscle metabolism disorder,glucocorticoid application,malnutrition,etc.,and the clinical therapeutic effect of existing therapies is not ideal.COPD plus sarcopenia belongs to the categories of lung swelling and flaccid paralysis categories in TCM.Based on the pectoral Qi(气)theory of TCM master ZHANG Xichun,and combined with the descriptions of generation and function of pectoral Qi in Yixue Zhongzhong Canxi Lu(《医学衷中参西录》),the author deeply explores new ideas of treating COPD plus sarcopenia in TCM,and believes that Qi deficiency and subsidence leads to systemic viscera gasilication function disorder,and endogenous phlegm and blood stasis is the fundamental etiology,with phlegm,blood stasis,and deficiency as the main pathogenesis.Qi deficiency and subsidence is root cause,and phlegm and blood stasis retardation is superficial symptom,and pectoral Qi deficiency and subsidence run through the whole course of the disease.From the aspect of the therapeutic principles of benefiting Qi and raising sunken Yang(阳),harmonizing Ying(营)and Wei(卫),regulating five Zang(脏)viscera simultaneously,facilitating Qi to dispel phlegm and blood stasis,the treatment of COPD in TCM is discussed in this paper,providing a comprehensive program with TCM characteristics and theoretical basis for the clinical diagnosis and treatment of the disease,and providing a valuable reference for improving the prognosis and quality of life of patients.

The pectoral Qi theoryChronic obstructive pulmonary diseaseSarcopenia

袁欣悦、苏洁琼、史依依、白丽、王盛隆

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山西中医药大学,山西 太原,030024

山西中医药大学附属中西医结合医院,山西 太原,030013

大气理论 慢性阻塞性肺疾病 肌少症

2024

中医临床研究
中华中医药学会

中医临床研究

影响因子:0.839
ISSN:1674-7860
年,卷(期):2024.16(32)