To Explore the Medication Rules and Formulation Characteristics of Traditional Chinese Medicine for Prevention and Treatment of Dry Eye Based on Data Mining
The clinical research literatures on the prevention and treatment of dry eye disease with traditional Chinese medicine orally were searched from CNKI,Wanfang and VIP databases.The prescriptions that met the inclusion criteria were standardized processing and the frequency of medi-cation was counted.SPSS series software was used for association rule molecule,cluster analysis and factor analysis of high-frequency drugs.The results showed that there were 305 prescriptions and 172 herbs in total,the drug efficacy is mainly to tonify deficiency and clear heat.The top ten herbs included Fructus Lycii,Chrysanthemi Flos,Ophiopogonis Radix,Rehmannia Glutinosa,Radix Gly-cyrrhizae,Radix Rehmanniae,Radix Paeoniae Alba,Radix Angelicae Sinensis,Poria cocos and Cortex Moutan.Association rule analysis showed that the Chrysanthemi Flos-Lycii Fructus was the most core drug pair.Nourishing yin and generating fluid,clearing away heat and moistening dryness are the basic treatment methods for dry eye disease.Qiju Dihuang Pills is the core prescription,and chrysanthemum-wolfberry fruit is the drug combination with the highest co-occurrence frequency,which can provide a reference for clinical prescription medication.
dry eye diseasetraditional Chinese medicinedata miningmedication rule
万方数据
维普
