首页|《消渴病古今名家验案全析》中糖尿病组方规律研究

《消渴病古今名家验案全析》中糖尿病组方规律研究

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为探讨古今名医治疗糖尿病的用药及组方规律,以期更好地指导临床.本文摘录了《消渴病古今名家验案全析》中糖尿病的治疗方剂,运用配伍密度分析、关联规则、因子分析、决策树模型等数据挖掘方法总结糖尿病治疗的组方规律.共纳入311首中药处方,涉及226味中药,累计使用3 315次.治疗糖尿病的中药以补虚类最多,清热类次之;药性以寒为主,药味多见苦、甘,且多入脾经、肾经、胃经.关联规则分析得到32项中药组合;因子分析得到5个公因子;决策树模型分析显示,以山药为自变量,最佳识别中药为黄芪.本研究基于数据挖掘发现了糖尿病治疗的高频中药,揭示了糖尿病治疗的组方规律,明确了糖尿病治疗的遣方用药模式,为该病的临床治疗提供了参考.
The Regularity of Prescriptions for Diabetes in"Comprehensive Analysis of Proven Cases of Ancient and Modern Famous Experts on Diabetes"
Objective:To explore the regularity of prescriptions in"comprehensive analysis of proven cases of ancient and modern famous experts on diabetes",so as to better guide clinical practice.Methods:The prescriptions for the treatment of diabetes in this book were extracted,The data min-ing methods such as compatibility density analysis,association rules,factor analysis,and decision tree model were used to summarize the regularity of prescription in the treatment of diabetes.Results A total of 311 prescriptions were included,involving 226 traditional Chinese medicines,with a total of 3315 times of usage.The traditional Chinese medicine treating diabetes were mostly tonics,fol-lowed by heat-clearing ones;and the main properties of them were cold,and the tastes were mostly bitter and sweet,and most of them entered the spleen,kidney and stomach meridians.32 combina-tions of traditional Chinese medicine were obtained by association rule analysis;while factor analysis got 5 common factors.Decision tree model analysis demonstrated that with Dioscoreae Rhizoma as an independent variable,the best recognized Chinese medicine was Astragali Radix.Conclusion:Based on data mining,this study discovered high-frequency traditional Chinese medicine for diabetes treatment,revealed the regularity of prescriptions,and clarified the prescription and medication mode for diabetes treatment,which could provide a reference for the clinical treatment.

comprehensive analysis of proven cases of ancient and modern famous experts on diabe-tesdiabetesdata miningDioscoreae RhizomaAstragali Radix

吴春兴、孟梅、刘海亮、秦后响、李丹丹

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滨州市中心医院,山东滨州 251700

烟台肺科医院,山东烟台 264001

浙江大学,浙江杭州 310027

杭州市第一人民医院,浙江杭州 310006

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古今名家验案全析 糖尿病 数据挖掘 山药 黄芪

2024

中央民族大学学报(自然科学版)
中央民族大学

中央民族大学学报(自然科学版)

影响因子:0.462
ISSN:1005-8036
年,卷(期):2024.33(3)