Canonical correlation analysis of quality of life and clinical indicators in patients with occupational chronic benzene poisoning
Objective To explore the correlation between the quality of life and clinical indicators in patients with occupational benzene poisoning,providing a basis for individualized and differentiated treatment to improve their quality of life.Methods A total of 62 patients diagnosed with occupational chronic benzene poisoning and hospitalized from January 2020 to August 2022 were studied.The SF-36 Health Survey was used to assess their quality of life,and routine clinical indicators of blood such as white blood cell count,red blood cell count,platelet count,absolute neutrophil count,and hemoglobin were collected from the patients.Canonical correlation analysis was used to analyze the correlation between quality of life and clinical indicators.Results The total average score of the SF-36 Health Survey of 62 patients was(37.48±19.58),which was lower than the norm.Canonical correlation analysis extracted one pair of canonical variables,showing a moderate correlation(r=0.684,P＜0.05).The first pair of canonical variables reflecting clinical indicators and demographic characteristics were mainly determined by body mass index(BMI),white blood cell count,and absolute neutrophil count,with standardized canonical correlation coefficients of-0.891,0.378,and-0.477,respectively;the first pair of canonical variables reflecting the quality of life were mainly determined by bodily pain,social functioning,emotional role,and physical functioning,with standardized canonical correlation coefficients of-0.482,-0.387,0.538,and-0.490,respectively.Conclusions There was a high and complex correlation between the quality of life and clinical indicators,such as routine blood examination indicators of patients.Clinicians should pay attention to these factors in treatment to comprehensively improve the mental health and quality of life of patients with occupational benzene poisoning.
benzene poisoningSF-36 Health Surveyclinical indicatorsquality of lifecanonical correlation
NETL
NSTL
万方数据
