中药新药与临床药理2024,Vol.35Issue(1) :152-157.DOI:10.19378/j.issn.1003-9783.2024.01.018

狗脊化学成分、药理作用及质量控制的研究进展

Research Progress on Chemical Constituents,Pharmacological Effects and Quality Control of Cibotii Rhizoma

郭忠静 李恩念 赵志敏 杨得坡 徐新军
中药新药与临床药理2024,Vol.35Issue(1) :152-157.DOI:10.19378/j.issn.1003-9783.2024.01.018

狗脊化学成分、药理作用及质量控制的研究进展

Research Progress on Chemical Constituents,Pharmacological Effects and Quality Control of Cibotii Rhizoma

郭忠静 1李恩念 2赵志敏 1杨得坡 1徐新军1
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作者信息

  • 1. 中山大学药学院,广东 广州 510006
  • 2. 广东远思南药生物科技有限公司,广东 平远 514699
  • 折叠

摘要

狗脊具有悠久的民间及临床应用历史,常用于治疗腰膝酸软、手足麻木等症.其化学成分主要包括糖及糖苷类、芳香族类、挥发油类、蕨素类、黄酮类、甾体类、吡喃酮类、氨基酸类和无机元素.药理学研究表明,狗脊具有抗氧化、抗炎、抗骨质疏松、胃肠保护、抑菌、保肝、抗癌、镇痛等作用.该文系统综述了狗脊化学成分、药理活性及质量控制的研究现状,可为狗脊的深入开发和合理使用提供参考.

Abstract

Cibotii Rhizoma has a long history of folk usage and clinical applications,which is commonly used to treat symptoms such as waist and knee soreness,numbness of hands and feet.Its chemical components mainly include sugars and glycosides,aromatics,volatile oils,pterosins,flavonoids,steroids,pyranones,amino acids and inorganic elements.Pharmacological studies have shown that Cibotii Rhizoma has antioxidant,anti-inflammatory,anti-osteoporosis,gastrointestinal protection,antibacterial,liver protection,anticancer,analgesic and other effects.This paper systematically reviews the research status of chemical constituents,pharmacological effects and quality control of Cibotii Rhizoma,which provides reference for the development and rational use of Cibotii Rhizoma.

关键词

狗脊/化学成分/药理作用/质量控制

Key words

Cibotii Rhizoma/chemical constituents/pharmacological effects/quality control

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基金项目

国家重点研发计划(2022YFD1600300)

南药产业技术体系建设项目创新团队建设项目(2021KJ142)

南药产业技术体系建设项目创新团队建设项目(2022KJ142)

出版年

2024
中药新药与临床药理
广州中医药大学

中药新药与临床药理

CSTPCD北大核心
影响因子:0.908
ISSN:1003-9783
被引量1
参考文献量28
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