秦皮甲素和秦皮乙素的药理研究进展
Research Progress in Pharmacology of Aesculin and Aesculetin
储正达 1蔡彬1
作者信息
- 1. 南京中医药大学无锡附属医院,江苏 无锡 214071
- 折叠
摘要
秦皮为一种传统中药,其毒性低、临床应用范围广,常被运用于治疗目赤肿痛、湿热泻痢、赤白带下、血崩不止等病症.药理研究发现香豆素类化合物是秦皮的主要活性成分,其中秦皮甲素和秦皮乙素最具代表性.众多的研究显示,秦皮甲素和秦皮乙素在抗菌、抗炎、抗肿瘤、抗氧化等方面展现出丰富的药理学活性,其潜在的开发利用价值日益受到关注.该文通过查阅国内外相关文献,对秦皮甲素和秦皮乙素的主要药理作用研究进行归纳,以期为秦皮的研发及临床运用提供参考依据.
Abstract
Cortex Fraxini,a kind of traditional Chinese medicinal,has low toxicity and wide clinical application.It is widely used to treat diseases such as swelling and pain of eye,damp-heat diarrhea,leucorrhea with reddish discharge,metrorrhagia,etc..Modern pharmacological studies have found that coumarin compounds are the main active components of Fraxini Cortex,among which aesculin and aesculetin are the most representative components.Numerous studies have reported that aesculin and aesculetin exhibit abundant pharmacological activities including antibacterial,anti-inflammatory,anti-tumor,antioxidant,and the potential development and utilization of these compounds has attracted increasing attention.This paper summarized the research progress of the main pharmacological effects of aesculin and aesculetin by reviewing the relevant literature at home and abroad.Our aim is to provide a reference for the drug development and clinical application of Fraxini Cortex.
关键词
秦皮/秦皮甲素/秦皮乙素/香豆素/研究进展Key words
Fraxini Cortex/aesculin/aesculetin/coumarin/research progress引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据