首页|劳绍贤辨治胃痞的数据挖掘分析和经验总结

劳绍贤辨治胃痞的数据挖掘分析和经验总结

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目的 分析劳绍贤教授辨治胃痞的用药规律.方法 收集劳绍贤教授于 2017 年 3 月至 2022 年 3 月期间治疗胃痞患者的有效处方,提取患者一般资料、主诉、诊断、辨证分型、处方等.采用Excel软件和古今医案云平台(V 2.3.7)工具,构建处方数据库,利用其数据挖掘功能对处方进行证型分析、中药使用频次和属性分析,以及药物关联规则分析、聚类分析等.结果 共纳入 272 首处方,涉及 164 味药物.中医证型以湿热证、气滞证为主;使用频次≥30 次的中药有 25 味,代表性药物为法半夏、甘草、陈皮、紫苏梗、木香;药性主要是温性、平性;药味主要为辛、苦、甘;药物主要归脾、胃、肺三经,其次是肝经;关联规则获得木香-紫苏梗、陈皮-紫苏梗、法半夏-陈皮等 23 个核心药对;聚类分析将药物分为 3 个组合,有理气除痞、祛湿化滞、清热解毒等功效.结论 劳绍贤教授治疗胃痞的核心处方为木香、紫苏梗、陈皮、法半夏、甘草、柿蒂、枳实、大腹皮;重在调畅中焦气机,脾胃同治,以理气除痞为主要治法,同时重视祛湿化滞、清热解毒类药物的应用,临床疗效显著,可供诊疗参考.
Data Mining Analysis and Experience Summary of LAO Shaoxian in the Treatment of Gastric Stuffiness(Weipi)
Objective To analyze the medication rules of Professor LAO Shaoxian in the treatment of gastric stuffiness based on syndrome differentiation.Methods The effective prescriptions for patients with gastric stuffiness treated by Professor LAO Shaoxian from March 2017 to March 2022 were collected,and the general information,chief complaints,diagnosis,syndrome differentiation and prescriptions of patients were extracted.Excel software and the ancient and modern medical records cloud platform(V 2.3.7)were used to construct the prescription database.Data mining function was used to carry out analysis of the syndrome type of prescription,analysis of the frequency and property of Chinese herbs,as well as association rule analysis and cluster analysis.Results A total of 272 prescriptions were included,involving 164 kinds of medicinal herbs.The main traditional Chinese medicine(TCM)syndrome types are damp-heat syndrome and qi stagnation syndrome.The frequency of 25 herbs was more than or equal to 30 times.The representative herbs is Pinellinae Rhizoma Praeparatum,Glycyrrhizae Radix et Rhizoma,Citri Reticulatae Pericarpium,Perillae Caulis and Aucklandiae Radix.The medicinal properties are mainly warm and flat.The medicinal flavors are spicy,bitter and sweet.The drug meridians mainly included the spleen,stomach and lung meridians,followed by the liver meridian.There were 23 core drug pairs obtained by association rules,such as"Aucklandiae Radix-Perillae Caulis","Citri Reticulatae Pericarpium-Perillae Caulis",and"Pinellinae Rhizoma Praeparatum-Citri Reticulatae Pericarpium".Clustering analysis of drugs can be divided into three combinations,which have the effects of regulating qi and relieving distension,resolving dampness,and clearing heat and detoxifying.Conclusion The core prescription of Professor LAO Shaoxian in the treatment of gastric stuffiness is Aucklandiae Radix,Perillae Caulis,Citri Reticulatae Pericarpium,Pinellinae Rhizoma Praeparatum,Glycyrrhizae Radix et Rhizoma,Kaki Calyx,Aurantii Fructus Immaturus and Arecae Pericarpium.It focuses on regulating qi movement of middle jiao and treating spleen and stomach simultaneously.The main therapeutic method is regulating qi and relieving distension.At the same time,attention should be paid to the application of dampness-dispelling and stagnation-removing,heat-clearing and detoxifying drugs.The clinical therapy of Professor LAO Shaoxian on gastric stuffiness is significant,which can be used as a reference for diagnosis and treatment.

gastric stuffinesstraditional Chinese medicine treatmentdamp-heat syndrome:qi stagnation syndromemedication ruledata miningexperience of famous doctorsLAO Shaoxian

王姝烨、杨泽虹、陈彦彤、段文韬、陶杨、李培武

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广州中医药大学,广东 广州 510405

广州中医药大学第一附属医院,广东 广州 510405

广州中医药大学第一附属医院重庆医院,重庆 400799

胃痞 中医药诊疗 湿热证 气滞证 用药规律 数据挖掘 名医经验 劳绍贤

广州中医药大学"双一流"与高水平大学学科协同创新团队项目广州中医药大学"双一流"与高水平大学学科后备人才培育项目青年岐黄学者项目

2021xk47国中医药人教发20207号

2024

中药新药与临床药理
广州中医药大学

中药新药与临床药理

CSTPCD北大核心
影响因子:0.908
ISSN:1003-9783
年,卷(期):2024.35(3)
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