首页|黄芪建中汤颗粒的成型工艺研究

黄芪建中汤颗粒的成型工艺研究

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目的 研究黄芪建中汤颗粒的最佳成型工艺.方法 以制备软材的难易程度、制粒的难易程度、颗粒成型性及溶化性为评价指标,正交试验法优化黄芪建中汤颗粒的成型工艺;以颗粒成型性、颗粒含水量为评价指标,筛选湿颗粒的干燥温度.结果 黄芪建中汤颗粒的最佳成型工艺:药物:可溶性淀粉:糊精为1:1:1,润湿剂为75% 乙醇,其用量为28%;湿颗粒的最佳干燥温度:60℃.结论 该研究优化的黄芪建中汤颗粒的成型工艺,其方法合理可行,可为黄芪建中汤颗粒的制备提供科学依据.
Study on Forming Process of Huangqi Jianzhong Decoction Granules
Objective To study the best forming process of Huangqi Jianzhong Decoction Granules. Methods Taking the difficulty of preparing soft materials and granulation,as well as formability and solubility of particles as evaluation indexes,this paper carried out orthogonal test to optimize the forming process of particles. The drying temperature of wet particles was screened by taking particle formability and water content as evaluation indexes. Results The optimum forming process of Huangqi Jianzhong Decoction Granules was as follows:the ratio of drug to the starch to the dextrin was 1:1:1,wetting agent was 75% ethanol,and its dosage was 28%. The optimum drying temperature of wet granules was 60 ℃. Conclusion In this study,the forming process of Huangqi Jianzhong Decoction Granules was optimized. The method was reasonable and feasible,which could provide scientific basis for the preparation of Huangqi Jianzhong Decoction Granules.

Huangqi Jianzhong Decoction Granulesextraction processorthogonal testforming process

刘杨、顾晋亿、姜雯钰、葛胜宇、金莉莉、关皎、朱鹤云

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吉林医药学院药学院,吉林吉林132013

延边大学药学院,吉林 延边 133002

黄芪建中汤颗粒 提取工艺 正交试验 成型工艺

2024

中药新药与临床药理
广州中医药大学

中药新药与临床药理

CSTPCD北大核心
影响因子:0.908
ISSN:1003-9783
年,卷(期):2024.35(11)