Objective To study the best forming process of Huangqi Jianzhong Decoction Granules. Methods Taking the difficulty of preparing soft materials and granulation,as well as formability and solubility of particles as evaluation indexes,this paper carried out orthogonal test to optimize the forming process of particles. The drying temperature of wet particles was screened by taking particle formability and water content as evaluation indexes. Results The optimum forming process of Huangqi Jianzhong Decoction Granules was as follows:the ratio of drug to the starch to the dextrin was 1:1:1,wetting agent was 75％ ethanol,and its dosage was 28％. The optimum drying temperature of wet granules was 60 ℃. Conclusion In this study,the forming process of Huangqi Jianzhong Decoction Granules was optimized. The method was reasonable and feasible,which could provide scientific basis for the preparation of Huangqi Jianzhong Decoction Granules.
关键词
黄芪建中汤颗粒/提取工艺/正交试验/成型工艺
Key words
Huangqi Jianzhong Decoction Granules/extraction process/orthogonal test/forming process
维普
万方数据