Study on the Mechanisms of Early-life Stress Regulation of Reward Circuits in Mediating Depression and the Intervention Strategies of Traditional Chinese Medicine
Study on the Mechanisms of Early-life Stress Regulation of Reward Circuits in Mediating Depression and the Intervention Strategies of Traditional Chinese Medicine
Abnormalities in the reward circuit play a key role in the onset and progression of depression. Early-life stress is a key risk factor for depression. However,how early-life stress affects the structure and function of the reward circuit,and its underlying mechanisms have not been fully elucidated. Traditional Chinese medicine(TCM)has shown remarkable efficacy in the treatment of depression and provides an effective alternative treatment program for depression. This paper summarizes the impacts of early-life stress on the structure and function of the reward circuit,as well as evaluates the potential intervention mechanisms and effects of TCM in this process,thus to provide theoretical support and new perspectives for further research and treatment of depression.
关键词
中医药/生命早期应激/奖赏环路/抑郁症/作用机制
Key words
Traditional Chinese medicine/early-life stress/reward circuit/depression/mechanism of action
维普
万方数据