首页|先天性心脏病儿童13价肺炎球菌多糖结合疫苗免疫效果及安全性的研究进展

先天性心脏病儿童13价肺炎球菌多糖结合疫苗免疫效果及安全性的研究进展

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先天性心脏病(congenital heart disease,CHD)儿童感染肺炎链球菌后发展为肺炎重症及死亡的风险较高,近年来,CHD 儿童 13 价肺炎球菌多糖结合疫苗(13-valent pneumococcal polysaccharide conjugate vaccine,PCV13)免疫效果相关研究被诸多医疗专家所关注.本文通过检索中国知网、维普、万方、Pubmed等数据库,就PCV13在CHD儿童中免疫效果及安全性相关研究进展进行综述,为CHD儿童PCV13接种提供参考依据.
Research progress on immune efficacy and safety of 13-valent pneumococcal polysaccharide conjugate vaccine in children with congenital heart disease
Children with congenital heart disease(CHD)are at high risk of developing severe pneumonia and death after being infected with Streptococcus pneumoniae.In recent years,research on the immune effect of 13-valent pneumococcal polysaccharide conjugate vaccine(PCV13)in children with CHD has attracted the attention of many medical experts.This article reviews the research progress on the immune effect and safety of PCV13 in CHD children by searching databases such as China National Knowledge Infrastructure(CNKI),VIP,Wanfang,Pubmed,etc.,providing reference for PCV13 vaccination in CHD children.

13-valent pneumococcal polysaccharide conjugate vaccineCongenital heart diseasePneumococcal pneumoniaImmune efficacySafety

张瑞、程琬然、陈琳琰、王卫平、冯勇、邓鹏飞

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上海市浦东新区疾病预防控制中心免疫预防科,复旦大学浦东预防医学研究院 上海 200136

13价肺炎球菌多糖结合疫苗 先天性心脏病 肺炎球菌性肺炎 免疫效果 安全性

上海市浦东新区卫生健康委员会重点学科上海市浦东新区疾病预防控制中心课题上海市浦东新区卫生健康委员会学科带头人培养计划上海市优秀青年人才项目

PWZxk2022-25PDCDC-2021-05PWRd2020-14GWV-10.2-YQ38

2024

职业与健康
天津市疾病预防控制中心 中华预防医学会

职业与健康

CSTPCD
影响因子:0.737
ISSN:1004-1257
年,卷(期):2024.40(11)