先天性心脏病儿童13价肺炎球菌多糖结合疫苗免疫效果及安全性的研究进展
Research progress on immune efficacy and safety of 13-valent pneumococcal polysaccharide conjugate vaccine in children with congenital heart disease
张瑞 1程琬然 1陈琳琰 1王卫平 1冯勇 1邓鹏飞1
作者信息
- 1. 上海市浦东新区疾病预防控制中心免疫预防科,复旦大学浦东预防医学研究院 上海 200136
- 折叠
摘要
先天性心脏病(congenital heart disease,CHD)儿童感染肺炎链球菌后发展为肺炎重症及死亡的风险较高,近年来,CHD 儿童 13 价肺炎球菌多糖结合疫苗(13-valent pneumococcal polysaccharide conjugate vaccine,PCV13)免疫效果相关研究被诸多医疗专家所关注.本文通过检索中国知网、维普、万方、Pubmed等数据库,就PCV13在CHD儿童中免疫效果及安全性相关研究进展进行综述,为CHD儿童PCV13接种提供参考依据.
Abstract
Children with congenital heart disease(CHD)are at high risk of developing severe pneumonia and death after being infected with Streptococcus pneumoniae.In recent years,research on the immune effect of 13-valent pneumococcal polysaccharide conjugate vaccine(PCV13)in children with CHD has attracted the attention of many medical experts.This article reviews the research progress on the immune effect and safety of PCV13 in CHD children by searching databases such as China National Knowledge Infrastructure(CNKI),VIP,Wanfang,Pubmed,etc.,providing reference for PCV13 vaccination in CHD children.
关键词
13价肺炎球菌多糖结合疫苗/先天性心脏病/肺炎球菌性肺炎/免疫效果/安全性Key words
13-valent pneumococcal polysaccharide conjugate vaccine/Congenital heart disease/Pneumococcal pneumonia/Immune efficacy/Safety引用本文复制引用
基金项目
上海市浦东新区卫生健康委员会重点学科(PWZxk2022-25)
上海市浦东新区疾病预防控制中心课题(PDCDC-2021-05)
上海市浦东新区卫生健康委员会学科带头人培养计划(PWRd2020-14)
上海市优秀青年人才项目(GWV-10.2-YQ38)
出版年
2024
NETL
NSTL
万方数据