摘要
目的 建立微孔滤膜中镉、铬、锰、锌、铜、铁、钙、镁、铯、铟、锶、铋、锗、钽、锆和锡16种金属及其可溶性化合物同时测定的职业卫生检测方法.方法 采用微孔滤膜采集工作场所空气中的16种金属及其可溶性化合物,硝酸溶液消解后转移至比色管定容,电感耦合等离子体质谱(inductively coupled plasma-mass spectrometry,ICP-MS)法同时测定16种金属及其可溶性化合物的质量浓度.结果 16种金属元素在0.00～1 000.00 g/L范围内线性关系良好,曲线的相关系数为0.999 7～1.000 0,检出限为0.10～3.11 g/L,定量下限为0.33～10.36 g/L;最低检出浓度为0.01×10-3～0.41×10-3 mg/m3,最低定量浓度为0.06×10-3～1.38×10-3 mg/m3(以现场采集75 L空气样品来计算);加标回收率为96.41％～104.18％,相对标准偏差为0.14％～3.14％;样品在室温下至少可稳定保存7 d再进行消解和测定.结论 本方法可优化程序和提高工作效率,并符合工作场所空气中化学物质测定方法的研制规范,可用于工作场所空气中镉、铬、锰、锌、铜、铁、钙、镁、铯、铟、锶、铋、锗、钽、锆、和锡16种金属及其可溶性化合物的同时测定.
Abstract
Objective To establish an occupational health detection method for simultaneous determination of 16 metals and their soluble compounds in microporous filter membranes,including cadmium,chromium,manganese,zinc,copper,iron,calcium,magnesium,cesium,indium,strontium,bismuth,germanium,tantalum,zirconium and tin.Methods A microporous filter membrane was used to collect 16 metals and their soluble compounds in the workplace air,and the nitric acid solution was digested and transferred to the colorimetric tube to determine the volume,and the mass concentration of 16 metals and their soluble compounds was determined by inductively coupled plasma-mass spectrometry(ICP-MS).Results The linear relationship between the 16 metal elements in the range of 0.00-1 000.00 μg/L was good,with a correlation coefficient of 0.999 7-1.000 0,the detection limit was 0.10-3.11 μg/L,and the lower limit of quantification was 0.33-10.36 µg/L.The minimum detection concentration was 0.01 × 10-3-0.41×10-3 mg/m3,and the minimum quantitative concentration was 0.06×10-3-1.38×10-3 mg/m3(calculated by collecting 75 L air samples on site).The recovery rate of spiked was 96.41％-104.18％,and the relative standard deviation was 0.14％-3.14％.The samples could be stably stored at room temperature for at least 7 days before digestion and determination.Conclusion This method can optimize the procedure and improve the work efficiency,and conforms to the development specifications of the determination method of chemical substances in workplace air,and can be used for the simultaneous determination of 16 metals and their soluble compounds in workplace air,including cadmium,chromium,manganese,zinc,copper,iron,calcium,magnesium,cesium,indium,strontium,bismuth,germanium,tantalum,zirconium and tin.
基金项目
广东省医学科学技术研究基金项目(B2021033)
NETL
NSTL
万方数据