Clinical Phenome and Pharmacophenome of Fengre(风热)Cold
Amid the modernization of traditional Chinese medicine(TCM),the emerging phenomics has become a new paradigm for the integration of TCM with western medicine.This study described how to construct a clinical phenome of Fengre(风热f)cold(FRC)based on the TCM syndrome and the syndrome-related phenotypic characteristics in western medicine.In addition,a large phenomic cohort of clinical FRC phe-nome and Yinqiaosan(银翘散)pharmacophenome was established according to the TCM principle of prescription corresponding with syn-drome.The phenomics of these cohorts with integrated multi-omic approaches may lay a scientific basis for the quantitative diagnosis and treatment of TCM syndrome and the evaluation of clinical efficacy and ultimately precise prevention and treatment of FRC.
PhenomicsFengre(风热)coldYinqiaosan(银翘散)TCMMetabonomicsPrecision medicine