Citespace Scientific Knowledge Map Analysis of Traditional Chinese Medicine for Postmenopausal Coronary Heart Disease
Objective:To analyze the current status,research hotspots,and future trends in traditional Chinese medicine(TCM)treatment of postm-enopausal coronary heart disease using CiteSpace,providing a reference for further research in this field.Methods:CNKI,Wanfang Data,VIP,SinoMed,PubMed,and WoSCC databases were used as sources of literature.Chinese and English research articles related to TCM treat-ment of postmenopausal coronary heart disease were retrieved from database inception to December 31,2021.Visual analysis was performed using CiteSpace on publication volume,authors,institutions,keywords,etc.Results:A total of 3 479 Chinese articles were retrieved,and after applying inclusion criteria,74 articles were eligible.Seven English articles were retrieved,but due to their limited number,they were not suit-able for bibliometric analysis and were excluded from visual analysis.The overall trend in Chinese publications showed fluctuations,with a consistently low annual publication volume.Authors with a high number of publications included Li Shuqin,Du Jun,Wu Yuzhou,and Wang Fengfei.Several Chinese TCM hospitals,integrated TCM and western medicine hospitals,and affiliated hospitals of TCM universities had high publication volumes,but the number of studies was limited,and collaboration was less intensive.Dezhou People's Hospital in Shandong Prov-ince had the highest publication volume among institutions.The top five co-occurring keywords were coronary heart disease,menopause,angi-na,estrogen,and postmenopausal.Keywords with betweeness centrality＞0.1 included coronary heart disease,postmenopausal,estradiol,men-opause,and estrogen.Cluster analysis identified eight main clusters:#0 menopause,#1 Bushen(补肾),#2 postmenopausal,#3 Xiongbi(胸痹),#4 bidirectional regulation,#5 elderly,#6 osteoporosis,and #7 myocardial enzymes.Burst keyword analysis revealed that Xiaoyao Powder(逍遥散)was the keyword with the highest burst strength.The timeline map indicated that keywords like"postmenopausal coronary heart disease","Buyishenqi(补益肾气)","Ziheche(紫河车)",and"estrogen"were frequently mentioned in Chinese publications from 1996 to 2007.After 2008,the focus shifted to TCM treatment methods,Shuganjieyu(疏肝解郁),Buyiganshen(补益肝肾),Ginkgo biloba leaf,coro-nary blood flow,vascular elasticity,pharmacology,and clinical efficacy.Conclusion:The study of the efficacy and mechanisms of TCM treat-ment for postmenopausal coronary heart disease is a recent hotspot.The liver and kidneys are considered the core treatment focus,with Buyi-ganshen,Shuganjieyu,and Ziyinshengjin(滋阴生津)being the primary therapeutic approaches.TCM is believed to have effects on regula-ting estrogen levels,lipid metabolism,and protecting vascular endothelium.
Postmenopausal womenCoronary atherosclerotic cardiopathyCiteSpacebibliometricsTraditional Chinese medicineVisual a-nalysis
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