Research Progress on Chemical Constituents and Anti-Tumor Effects of Musk
Musk is a valuable traditional Chinese medicine with a long history of medicinal use and proven efficacy,possessing significant medicinal and economic value.It primarily comprises macrocyclic ketones,pyridine alkaloids,steroids,polypeptide proteins,aromatic heterocycles,and other chemical constituents.Research on the pharmacology of musk and its constituents has mainly focused on its anti-inflammatory,cardio-tonic,and anti-tumor properties.Moreover,traditional Chinese medicine compound preparations that contain musk,such as Xihuang(西黄)Pill,Liushen(六神)Pill,and Babaodan(八宝丹),are widely used in clinical practice,particularly as adjuvant therapy for anti-tumor treat-ment.This review summarized the chemical constituents,anti-tumor and toxicological effects of musk,as well as the clinical applications of compound preparations of musk in cancer prevention and treatment,so as to provide guidance for the future development and utilization of musk and its compound preparations and encourage further investigation into its anti-tumor efficacy.
MuskMacrocyclic ketonesAnti-tumorTraditional Chinese medicine compoundXihuang(西黄)Pill