Research Summary on Chemical Components,Pharmacological Effects,and Q-Markers of Blaps rynchopetera Fairmaire
Blaps rynchopetera Fairmaire is a traditional insect drug with both medicinal and edible values,with the effects of Baihuojiedu(败火解毒),Ruanjiansanjie(软坚散结),Xiaozhongzhitong(消肿止痛),and Xifengdingjing(息风定惊).It has attracted much attention because of the anti-tumor activity.In recent years,scholars have gradually expanded and updated their research on B.rynchopetera in multiple as-pects.The results have shown that B.rynchopetera has antimicrobial,anti-inflammatory,antioxidant,immunomodulatory,liver-protecting,pain-relieving,scar hyperplasia-inhibiting,and anemia-alleviating activities,demonstrating a wide application prospect.This study systematically summarized the chemical components and pharmacological effects of B.rynchopetera,and then predicted the quality markers(Q-markers)of B.rynchopetera from the aspects of specificity,effectiveness,measurability,and clinical efficacy of chemical components.It is suggested that protocatechuic acid,hydroxytyrosol,rynchopeterine A-I,blapsins A and B,tridecane,and 3-methylbutyric acid can be used as the candidate Q-markers of B.rynchopetera.The summary aims to provide a basis for establishing the quality evaluation system and for the further research and rational utilization of B.rynchopetera.
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