非编码RNA在中医药领域的研究现状
Non-Coding RNAs Used in Traditional Chinese Medicine:A Review
杨雨灿 1詹秀琴 1钱进军1
作者信息
- 1. 南京中医药大学医学院·整合医学学院,南京 210023
- 折叠
摘要
非编码RNA(ncRNA)是一类能转录但不编码蛋白质,且具有特定功能的RNA分子的统称,包括多种不同类型,参与多种生理病理过程.其中,在中医药研究领域对微小RNA(miRNA)、环状RNA(circRNA)与长非编码RNA(lncRNA)探讨相对多见,主要包括研究中医药治疗疾病的分子机制、探讨中医证候类型的微观分子本质以及研究中药的跨界调控三个方面,本文对其进行归纳总结,以期为中医药的传承与创新发展,中医药的现代化、世界化提供参考与依据.
Abstract
Non-coding RNAs (ncRNAs) are a class of RNA molecules that can be transcribed with little or no protein coding potential and have specific functions in diverse pathological and physiological processes.Among them,microRNAs (miRNAs),circular RNAs (circR-NAs),and long non-coding RNAs have been extensively investigated in traditional Chinese medicine (TCM).The available studies in this field mainly focus on the molecular mechanism of TCM treatment,the microscopic molecular nature of TCM syndromes,and the regulatory effects of Chinese medicinal materials.This paper reviews the relevant studies,aiming to provide a basis for the inheritance,innovative devel-opment,modernization,and globalization of TCM.
关键词
微小RNA/环状RNA/长非编码RNA/中医药/分子调控Key words
MiRNA/CircRNA/LncRNA/Traditional Chinese medicine/Molecular regulation引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据