摘要
冬虫夏草是一种传统名贵补虚药,从《本草备要》载"甘平,保肺益肾,止血化痰",至现行《中国药典》载"补肺益肾,止血化痰"等,历代中医典籍多有相关论述.百令胶囊是由冬虫夏草菌丝体低温发酵制成的菌粉胶囊,与天然冬虫夏草成分相似,传统"补肺益肾"功效明确.故重点围绕该功效对其肺部、肾脏、生殖系统和甲状腺等方面的临床应用以及主要活性成分进行综述,并进一步分析了百令胶囊的开发现状、研究局限及应用前景,以期为拓展百令胶囊的临床应用和深入的生物学基础研究提供可能的参考.
Abstract
Cordyceps is a traditional,valuable deficiency-tonifying drug.From the description in the Essentials of Materia Medica(Ben Cao Bei Yao)that"(Cordyceps is)sweet and neutral,and can tonify lungs and nourish kidneys,stop bleeding,and dissolve phlegm"to its entry in the current edition of Chinese Pharmacopoeia,which states that"it can tonify lungs and nourish kidneys,stop bleeding,and dissolve phlegm",Cordyceps has been extensively discussed in classical TCM literature across generations.Bailing(百令)Capsules are made from the myceli-um of Cordyceps sinensis fermented at low temperatures,with a composition similar to that of natural Cordyceps,and the traditional effects of"tonifying lungs and nourishing kidneys"are definite.This paper reviewed the clinical applications of Bailing Capsules in relation to the lungs,kidneys,reproductive system,and thyroid,focusing on its main active ingredients.Additionally,it further analyzed the current development status,research limitations,and application prospects of Bailing Capsules,aiming to provide a possible reference for expanding the clinical use and deepening the biological research of Bailing Capsules.
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