Clinical Study of the Xingnao Kaiqiao Acupuncture Method Combined with Bushen Huatan Huoxue Formula in Treating Acute Cerebral Infarction with Wind-Phlegm Stasis Syndrome
Objective:To investigate the clinical efficacy of the Xingnao Kaiqiao acupuncture method combined with the Bushen Huatan Huoxue formula in treating acute cerebral infarction with wind-phlegm stasis syndrome.Methods:A total of 106 patients who had acute cerebral infarction with wind-phlegm stasis syndrome treated at Sun Simiao Hospital of Beijing University of Chinese Medicine from January 2021 to December 2023 were selected.The patients were randomly divided into the acupuncture group and the combined group,with 53 cases in each group.Both groups received conventional Western medical treatments,including anticoagulation,microcirculation improvement,blood pressure control,neuroprotection,oxygen therapy,and cardiac monitoring.The acupuncture group received the Xingnao Kaiqiao acupuncture treatment,while the combined group received the Bushen Huatan Huoxue formula orally in addition to the acupuncture treatment.The TCM syndrome scores,neurological function indicators,hemodynamic parameters,neurological and motor function,daily living ability scores,clinical efficacy,and adverse reactions were observed in both groups.Results:After treatment,the TCM syndrome scores,NIH Stroke Scale(NIHSS)scores,glial fibrillary acidic protein(GFAP),neuron-specific enolase(NSE),S100β protein,time-to-peak(TTP),and resistance index(RI)levels in both groups were significantly lower than before treatment(P＜0.05),with the combined group showing lower levels than the acupuncture group(P＜0.05).After treatment,the levels of serum nerve growth factor(NGF),cerebral blood volume(CBV),mean blood flow(Qmean),simplified Fugl-Meyer assessment(FMA)scores,and Barthel Index(BI)scores in both groups were significantly higher than before treatment(P＜0.05),with the combined group showing higher levels than the acupuncture group(P＜0.05).The overall effective rate in the combined group was higher than that in the acupuncture group(P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion:The Xingnao Kaiqiao acupuncture method combined with the Bushen Huatan Huoxue formula in treating acute cerebral infarction with wind-phlegm stasis syndrome can reduce TCM syndrome scores,alleviate clinical symptoms,increase cerebral blood flow,improve neurological function,and enhance clinical efficacy with high safety.
万方数据
维普
