Pharmacological Mechanisms and Pharmacokinetic Research Progress of the Antitumor Effects of Hedyotis Diffusa
Hedyotis diffusa has the effects of clearing heat and detoxifying,reducing abscesses,and dissipating nodules.Flavonoids and terpenoids are its main chemical components that exert antitumor effects,showing significant inhibitory effects on lung cancer,liver cancer,breast cancer,colorectal cancer,etc.Its mechanisms are closely related to the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.Current pharmacokinetic research on Hedyotis diffusa mainly involves individual monomer components and cannot fully reflect its pharmacokinetic characteristics.This article reviews the recent research status of the antitumor effects and pharmacokinetics of Hedyotis diffusa by searching Chinese and English databases at home and abroad.The aim is to lay a foundation for subsequent research on the pharmacokinetic behavior of Hedyotis diffusa using a multi-component integration method and to provide a reference for the research,development,and clinical application of Hedyotis diffusa.
万方数据
维普
