Progress of Traditional Chinese Medicine in Anti-Acute Lung Injury Effect Based on TLR-4 Signaling Pathway
Acute lung injury is clinical common critical disease and its pathogenesis is complicated and the mortality is high.Toll-like receptor 4 (TLR-4) signaling pathway is closely related to the inflammatory reaction and plays an important role in the pathogenesis of ALI.In recent years,studies have found that some traditional Chinese medicine compound and active ingredients could protect and treat ALI through regulating the TLR-4 signaling pathway.In this pa per,we reviewed TLR-4 signaling pathway,the role of TLR-4 in ALI and the research progress of traditional Chinesemedicine in the prevention and treatment of ALI via TLR-4 signaling pathway.