Current Advances in Understanding Neuroprotective Effect of Wumei(Mume Fructus)in Neurodegenerative Diseases
Neurodegenerative diseases are global public health problems that seriously affect the quality of human life in the 21st century.The incidence of neurodegenerative diseases is increasing year by year and currently there is a lack of effective ther-apeutic drugs.Wumei(Mume Fructus)is one of the oldest herbal and health foods commonly used in Asian countries.It contains a variety of active ingredients such as organic acids,flavonoids and polysaccharides.It has multi-target,multi-pathway neuro-protective effects,such as anti-oxidative stress,mitochondrial protection,anti-inflammatory and anti-platelet aggregation.Wumei(Mume Fructus)shows a good application prospect in the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease,vascular dementia and Parkinson's disease.This paper reviewed the research on the active components and neuroprotective mechanism of Wumei(Mume Fructus)in treating various neurodegenerative diseases at home and abroad,in order to provide new research ideas for the clinical treatment of neurodegenerative diseases.
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